Richter Gedeon Vegyeszeti Gyar Rt

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Tavkozlesi Kutato Intezet

Lajos Kovacs

Tibor Keve

Bela Stefko

Gabor Megyeri

Laszlo Szporny

Ferenc Trischler

Erik Bogsch

Maria Gazdag

Gyorgy Dobo

Geza Ivanyi

Eva Palosi

Csaba Szantay

Gyorgy Hajos

Lajos Szabo

Bela Kiss

Lajos Kisfaludy

Erzsebet Lapis

Lajos Dancsi

Istvan Laszlovszky

Janos Galambos

Dora Groo

Laszlo Denes

Karola Jovanovics

Istvan Schon

Csaba Lorincz

Katalin Nogradi

Erno Tyihak

Gyorgy Szabo

Katalin Honty

Eszter Dezseri

Miklos Low

Gabor Szepesi

Karoly Lapis

Imre Peter

Bela Szende

Olga Nyeki

Lajos Balaspiri

Laszlo Varga

Vince Varro

Botond Penke

Bela Szarvady

Anna Kassai Nee Zieger

Laszlo Kopper

Imre Juhasz

Kalman Vargha

Karoly Haszmann

Nathanael Nichols

Sandor Janoskuti

Kalman Kovacs

Peter Pallai

Janos Lonovics

Judit Low, Nee Kaloczy

Andreas Jeney

Tamas Berhardt

Karoly Simon

Iidiko Berhardt

Anna Kassia Nee Zieger

Gizella Lorant

Zsuzsanna Muck

A picture frame for adjustably surrounding a picture. The inventive device includes a plurality of corner members each having a projecting leg extending therefrom. Each corners member is configured to adjustably receive therethrough the projecting leg of an adjacent corner member such that four corner members can be coupled together to form a frame adjustable to a desired size.

Adjustable frame

The invention relates to a new process for obtaining tissue-protective devices of bone surgery implants prepared from a medical-purity metal, titanium and/or a titanium-base microalloy containing at least 98% by weight of titanium, by establishing a biocompatible (tissue-protective) coating on the metal surface by anodic oxidation after degreasing and chemical or electrochemical etching, which comprises carrying out the anodic oxidation of the etched implant surfaces in an aqueous solution of a phosphate concentration lower than 20% by weight with a current density of 2 to 50 mA/cm.sup.2 until reaching a voltage of at least 105 V, then, after washing to ion-free, heat-treating the thus-oxidized implants at a temperature between 120.degree. C. and 750.degree. C. for 5 to 120 minutes, and repeating once or twice the anodic oxidation and heat-treatment with the phosphate concentration, current density and temperature values as given above for the first step.

Process for obtaining tissue-protective implants prepared from titanium

The present invention relates to a process for the preparation of high purity crystalline peptides Arg Lys Asp hydrate acetate and Arg Lys Asp Val from crude, amorphous peptides Arg Lys Asp and Arg Lys Asp Val hydrate acetate. The process is characterized in that

High purity crystalline peptides arglysasp and arglysaspval and a

The invention relates to novel 2-halogenated 8- and 1,8-substituted ergolene derivatives of the formula (I) and the acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the formula (I) ##STR1## wherein X stands for a halogen;

2-Halogenated-8- and 1,8-substituted ergolenes

The invention relates to a novel process for the halogenation in 2-position of ergot alkaloids. The process is characterized by that as a halogenating agent a system consisting of dimethylsulfoxide, a trialkylhalosilane or triarylhalosilane and optionally a hydrogen halide is used.

Process for the preparation of 2-halogenated ergoline derivatives

The invention relates to a novel process for the preparation of 2-bromo-.alpha.-ergocryptine and its acid addition salt by brominating .alpha.-ergocryptine in such a way that the bromination is carried out at room temperature by using a dimethylsulphoxide-hydrogen bromide mixture containing no more 0.02% of water and, if desired, converting the thus-obtained 2-bromo-.alpha.-ergocryptine to an acid addition salt in a known manner.

Process for the preparation of 2-bromo-.alpha.-ergocryptine

There are disclosed pharmaceutical compositions comprising at least one cytostatic agent and N.sup..epsilon. -trimethylthyllysin or a pharmaceutically acceptable salt thereof, optionally in association with conventional pharmaceutical carriers and other additives. The new compositions possess a reduced toxicity compared with the cytostatic agents administered alone.

Pharmaceutical compositions and process for the preparation of same

A process for the preparation of alkaloids of the leurosine type having the formula I ##STR1## and the acid addition salts thereof. In the formula I R is hydrogen or methyl. The compounds prepared according to the invention are known compounds showing cytostatic activity.

Process for the preparation of alkaloids of the leurosine type

A process for the preparation of L-aspartyl-(O-sulfato-L-tyrosyl)-L-methionyl-glycyl-L-tryptophyl-L-methion yl-L-aspartyl-L-phenylalanine amide, which comprises treating the protected octapeptide amide of the general formula (II) ##STR1## wherein X is BOC, Cbz or Ddz,

Process for the preparation of the cholecystokinin-pancreozymin

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Budapest, Hungary

Lajos Kovacs