Industrial Technology Research Institute

Genhealth Pharma Co., Ltd.

Lain-Tze Lee

Hui-Ping Tsai

Ying-Chu Shih

Jir-Mehng Lo

Tien-Soung Tong

Shau-Feng Chang

Yi-Ching Lee

Cheng-Yu Lee

I-Hong Pan

Kuo-Kuei Huang

Zong-Keng Kuo

Ying-Fei Tsai

Jui-Hung Yen

Yi-Wen Lin

Pi-Tsan Huang

Mei-Hui Chen

Shu-Fen Huang

Chih-Hung Chen

Hsin-Hsin Shen

On Lee

Chu-Hsun Lu

Chen-Fang Chung

Chih-Peng Liu

Cheng Hua Lin

Chrong-Shiong Hwang

Yen-Chun Chen

Ting-Shou Chen

Chia-Mu Tu

Hsin-Chieh Wu

Shu-Jiau Chiou

Meng-Nan Lin

Jennline Sheu

Yuan-Jang Tsai

Hsin-Jan Yao

Jenn-Line Sheu

Mei-Hueih Chen

Hsi-Ho Chiu

Ching-Huai Ko

Shao-Chan Yin

Jaw-Ji Tsai

Ling-Mei Wang

Hui-Ju Liang

Kuei-Tai Lai

Ying-Ying Wu

Li-Jie Hsu

Nai-Yun Hu

Ling-Meei Tsay

Li-Syuan Jian

Bie-Shung Tsai

Rong-Ming Lyu

Sue-Fen Jiang

Sheau-Ni Su

Nai-Yun Hsu

Shih Cheng Shen

Yih-Loong Lai

Jinun-Ban Yeh

Jinun B Yeh

Chin-Wei Liu

Shih-Hung Liu

Wan-Chun Liu

The present invention provides a novel compound for effectively preventing nerve damage and protecting nerves, and a preparation method thereof. Besides, the present invention also provides a pharmaceutical composition comprising the novel compound, and a use of the novel compound for preventing nerve damage and protecting nerves.

Nerve damage preventing and nerve protecting compounds, preparation method thereof, pharmaceutical composition thereof, and their use

The present invention discloses a novel 3-aryl-2-propen-1-one series derivative and the synthesis processes thereof. Besides, the present invention also discloses the series derivative as a pharmaceutical composition and their use for promoting myocardial regeneration.

Myocardial regeneration promoting compounds, preparation method thereof, and pharmaceutical composition

A method for treating liver fibrosis. The method includes administering to a subject suffering from liver fibrosis a pharmaceutically active extract obtained from aspecies. Also disclosed is a method for regenerating liver tissue and a method for improving a liver function.

Boehmeria extract and its use in treating liver diseases

An extract ofsp. in use of arthritis treatment is provided. The extract ofsp. and an active ingredient contained therein, antofine, are applicable to a method, pharmaceutical composition and dietary supplement for treatment of arthritis. A mass production of antofine from plant extracts is also provided.

[object Object]

The disclosure provides a method for treating hepatitis C, including: administering an effective amount of a proanthocyanidins oligomer to a subject in need, wherein the structure of the proanthocyanidins oligomer is shown as Formula (I): and in Formula (I), N is an integer of about 1-18.

Method for treating hepatitis C

A pharmaceutical composition for preventing or treating hepatitis C is provided, including oleanolic acid derivatives as an active ingredient and a pharmaceutically acceptable carrier. A method for preventing or treating hepatitis C in a subject in need thereof is also provided by administering the subject the pharmaceutical composition given above.

Pharmaceutical composition and method for preventing or treating hepatitis C

A method for treating or relieving inflammatory bowel disease (IBD) is provided, including administering an extract ofas an active ingredient to a subject. Themay be selected from the group consisting ofand a combination thereof.

Method for treating or relieving inflammatory bowel disease

A composition used for skin whitening includes: an effective amount of spermidine derivative, wherein a structure of the spermidine derivative is shown as Structure (I): where R1-R5 individually includes H, OH, or OCHand at least one of R1-R5 is OH, and the spermidine derivative has tyrosinase inhibition activity; and a cosmetically or pharmaceutically acceptable vehicle, wherein the composition used for skin whitening whitens skin.

Composition used for skin whitening, plant extracted skin whitening composition and composition having a skin whitening effect

The invention provides an anti-hepatitis C composition including: an effective amount of limonoid compound, wherein the structure of the limonoid compound is shown as Structure (I): where R1 comprises H or OAc and R2 comprises H or COCH(CH); and a pharmaceutically acceptable carrier or salt, and the anti-hepatitis C composition is used for inhibiting hepatitis C virus or treating hepatitis C. The invention also provides a method for treating hepatitis C and a method for preparing a drug for inhibiting hepatitis C viruses or treating hepatitis C.

Anti-hepatitis C composition and method for preparing drug for inhibiting hepatitis C viruses or treating hepatitis C

A pharmaceutical composition with an immunomodulating function is provided, including an extract ofobtained by grinding the, adding the groundto a solvent and isolating the extract from the solvent, wherein thecomprisesand Bupleurums with at least one of the nucleotide sequences selected from a group consisting of SEQ ID NOs. 1&#x2dc;6 and a nucleotide sequence with no more than 1% of the nucleotide sequence divergences of SEQ ID NOs. 1&#x2dc;6, or combinations thereof.

Pharmaceutical composition with immunomodulating function

The invention is related to novel azulene-oxindole compounds having formula (I) shown below, wherein one of R, Rand Rrepresents a moiety of formula (II), each of Aand Aindependently is nitrogen, oxygen or sulfur, each of the others of R, R, R, R, R, R, R, R, R, R, R, R, R, and Ris as recited in the specification. The novel compound potentially inhibits multiple kinases and thus can be used to treat some disease like cancer or inflammatory. 

Azulene-oxindole compounds as multiple-kinase inhibitors and useful as anticancer agents

Pharmaceutical compositions for treating immunological disorders and the preparing method of the same are disclosed, which include alcohol extracts of(schw) Wolf, and. The compositions are manufactured by novel procedures consisting of decocting using specific concentration ranges of alcohol, filtering, regulating pH value, purifying, concentrating, proportionally mixing, and making a granule powder from lyophilized extract. This invention used both in vitro and in vivo assays to evaluate therapeutic effects of specific combination of herbal plant extracts. The combination of herbal extracts has been able to maximize the anti-inflammatory activity and regulate the secretion of cytokines such as eotaxin and IL-4. When the pharmaceutical composition of the present invention is used for asthma, it can relieve coughs, resist airway allergic inflammation reactions, improve the pulmonary functions, reduce allergen specific IgE in bloods, stabilize elasmatoblasts, and stop the attacks from asthma.

Herbal composition for treating allergic disorders and method for making the same

Anthraquinone compound

An aqueous two-phase system for extracting glycosides from a herb includes the extractive solution, about 5 wt %-30 wt % of salt, about 5 wt %-30 wt % of polyol and selectively about 0 wt %-30 wt % of alcohols. The salt can be dihydrogen phosphate, hydrogen phosphate and phosphate or a mixture thereof, and it also can be sulfates, chlorides, oxalates, or acetates. In addition, a process for extracting glycosides using an aqueous two-phase system is disclosed. The procedures includes preparation of extractive solution, concentration, phase separation, drying, washing with solvent, cooling, filtration and drying of the final products.

Process for extracting glycoside using an aqueous two-phase system

A method for synthesizing .DELTA..sup.3 -7-substituted amino desacetoxy cephalosporanic acid from a penicillin sulfoxide or its alkylsilylated ester derivative is provided. According to the method, penicillin sulfoxide is heated in the presence of an organic ammonium salt catalyst and a copolymer composed of dimethylsilane and urea units until formation of the cephalosporanic acid occurs by ring expansion reaction. The copolymer functions both as a dehydrating agent for removing the water by-product generated from the reaction as well as an esterifying agent for converting penicillin sulfoxide into its dimethylsilyl ester derivative. The method of the invention produces high yields of the cephalosporanic acid and avoids the need for excess dimethylsilyating agents.

Method for the preparation of .DELTA..sup.3 -7-substituted amino

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Hsinchu, Taiwan

Lain-Tze Lee