Macau University of Science and Technology

Lai Han Elaine Leung

Liang Liu

Xiao Jun Yao

Ying Li

Jia Hui Xu

Qian Qian Wang

Xing Xing Fan

Chun Xie

One embodiment is a method of treating cancer. The method includes administering a therapeutically effective amount of a compound to a patient. The compound is represented by Formula I: 

Methods of treating cancer

One embodiment relates to a method of treating lung cancer by administering a compound of formula I to a patient. Another embodiment relates to a method of treating cancer with a KRAS mutation that includes administering to a patient the compound with the following formula I: 

Method of treating lung cancer

One example embodiment relates to a method of treating non-small cell lung cancer by administering a compound of formula (I) to a patient. Another example embodiment relates to a method of inhibiting progress of tumor growth in a patient with cancer, wherein tumor cells of the cancer have a mutant V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) gene, and the method includes administering to the patient the compound with the following formula I: 

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Macau, China

Lai Han Elaine Leung