C. R. Bard, Inc.

L Ven Raman

John R Fagan

Gerry D Ouellette

George Duval

Lex P Jansen

John A Wright

Jack Fagan

An elongate flexible wire-like medical device, such as a guidewire for use with a catheter, is formed with a shaft in which the difference between the magnitude of the tensile yield stress and compressive yield stress of the shaft is substantially reduced. The guidewire exhibits superior kink resistance without compromising other desirable characteristics and enables a guidewire to be made in a smaller diameter without loss of performance. The guidewire shaft may be formed from a precipitation hardenable alloy such as an alloy of nickel, cobalt, molybdenum and chromium (MP35N and Elgiloy), 455PH stainless steel or stainless steel alloy 1RK91. Also disclosed is a process for increasing the modulus of elasticity of an alloy of nickel, cobalt molybdenum and chromium. Further, the disclosure relates to an improved management and manufacturing process for constructing the tip of a medical guidewire.

High performance wires for use in medical devices and alloys therefor

A device for the percutaneous transluminal repair of septal defects is disclosed. The device comprises first and second expandable occluders fastened to each other, each occluder including a framework having a central hub with elongated struts radiating therefrom. The struts are constructed such that they have a resistance to fatigue that exceeds the maximum fatigue stresses to which the struts will be subjected over a prolonged period in vivo. As such, the device exhibits a significantly decreased likelihood of metal fatigue failures after prolonged exposure in vivo.

Occluder for repair of cardiac and vascular defects

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Framingham, MA, United States of America

L Ven Raman