Novartis Ag

Eyesense Ag

Addition Technology, Inc.

L Lawrence Chapoy

Dawn A Smith

Frank Chang

Arturo Norberto Medina

Michael Hugh Quinn

Angelika Maria Domschke

John B W Lett

William M Flynn

William Rovani

Arturo Noberto Medina

The invention provides a silicone hydrogel contact lens including a hydrolyzable units. The hydrolyzable units can be converted by hydrolysis into a hydrophilic units which is capable of imparting the silicone hydrogel contact lens a hydrophilic surface without post-curing surface treatment. The invention also provides an actinically crosslinkable prepolymer including hydrolyzable units and use of the prepolymer of the invention. In addition, the invention provides a method for making wettable silicone hydrogel contact lens without posterior surface treatments other than hydrolysis.

Silicone-containing polymeric materials with hydrolyzable groups

A pre-formed intrastromal corneal insert for use in treating Keratoconus and similar dystrophies and methods of using the same. An intrastromal insert of the present invention comprises a biocompatible polymer and may be used to adjust corneal curvature, thereby correcting vision abnormalities caused by disease or other surgical procedures. The insert may be comprised of a circular or semi-circular ring shape or a portion of a ring, or 'arc', encircling the anterior cornea within the frontal circumference of the cornea. The insert may be used in multiples to form complete arcs or to form constructs of varying thicknesses. The insert of the present invention possesses a cross section that results in a low scattering level of light.

Pre-formed intrastromal corneal insert for corneal abnormalities or dystrophies

This invention is generally related to a biocompatible sensor for detecting/measuring sugar, especially glucose, in an ocular fluid in a non-invasive or minimally invasive manner and a method for using the biocompatible sensor. A biocompatible sensor of the invention comprises, consists essentially, or consists of an ophthalmic device comprising a molecular sensing moiety which interacts or, reacts with sugar to provide an optical signal which is indicative of sugar level in an ocular fluid.

Ophthalmic sensor

A contact lens is disclosed having a front surface and a back surface. The lens contains a continuously varying aspheric surface on one or more of these surfaces.

Multifocal contact lens with aspheric surface

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Barrington Hills, IL, United States of America

L Lawrence Chapoy