Abl Bio Inc.

Legochem Biosciences, Inc.

Kyungjin Park

Yangsoon Lee

Byungje Sung

Yeunju Kim

Donghoon Yeom

Jinhyung Ahn

Daehae Song

Juhee Kim

Bora Lee

Hyejin Chung

Eunsil Sung

Youngdon Pak

Kyeongsu Park

Jiseon Yoo

Eunyoung Park

Yong-Gyu Son

Jaehyun Eom

Jinwon Jung

Dongin Kim

Sang Hoon Lee

Yong Zu Kim

Ho Young Song

Ju Young Lee

Jeiwook Chae

Sung Min Kim

Hyoung Rae Kim

Kyung Eun Park

Chang Sun Lee

Dae Hyuck Kang

Yun-Hee Park

Jaeho Jung

Ji Hye Oh

Uijung Jung

Seawon Ahn

Minji Park

Hyeun Joung Lee

Ui-Jung Jung

Eunjung Kim

JinWon Jung

Sungwon An

Hyun Min Ryu

Jaehyoung Jeon

Myeong Joon Kim

Junhyun Jeong

Sang-Jun Ha

Yoseob Lee

Mikyung Chang

Weonkyoo You

Youngeun Hong

Ji-Na You

Nara Han

Young-Jae Yang

Ju Yuel Baek

Provided are an antibody or antigen-binding fragment thereof that specifically binds to a B-cell maturation antigen (BCMA), a method of preparing the same, and use thereof. Accordingly, these can be utilized in effectively preventing or treating cancers.

Anti-BCMA antibody and use thereof

The present invention discloses an anti-ROR1 antibody specifically recognizing human and mouse ROR1. The monoclonal antibody can be usefully used for cancer targeting treatment including detection of various cancer expressing ROR1 through specific binding, and drug delivery to specific cancer, etc. as well as a cancer therapeutic agent, by inhibiting tumors.

Anti-ROR1 antibody and use thereof

The present invention relates to a bi-specific antibody that specifically binds to alpha-synuclein and IGF1R, and use of the bi-specific antibody for treating or diagnosing synucleinopathies associated with alpha-synuclein or alpha-synuclein aggregates. The IGF1R portion of the bi-specific antibody acts as a shuttle to penetrate the blood brain barrier, allowing the alpha-synuclein portion to exert its action in the brain. Further, the half-life of the bi-specific antibody may be extended to maintain efficacy over time.

Bispecific antibody to alpha-synuclein/insulin-like growth factor 1 receptor and use thereof

Provided is an anti-B7-H3 antibody specifically recognizing a B7-H3, which can be usefully as a cancer therapeutic agent, as having an inhibitory activity of an immune checkpoint which induces antibody-dependent cell-mediated cytotoxicity and T cell activation inhibited by B7-H3. In particular, the antibody having the inhibitory activity of an immune checkpoint can be used in combination with other immunoantibody therapeutic agents. In addition, it can be usefully used for cancer targeting treatment including detection of various cancers expressing B7-H3 through specific binding to B7-H3, and drug delivery to specific cancer, etc.

Anti-B7-H3 antibody and use thereof

The present invention relates to new antibody-drug conjugates (ADCs) targeting ROR1, active metabolites of such ADCs, methods for preparation of such ADCs, uses for such ADCs in treatment and/or prevention of illnesses, and uses for such ADCs in production of drugs for treatment and/or prevention of diseases, more specifically diseases associated with over-expression of ROR1, for example cancer. More specifically, the present invention relates to an antibody-drug conjugate comprising an antibody that binds to ROR1 or an antigen-binding fragment thereof, and a pharmaceutical composition comprising the same.

Antibody-drug conjugate comprising antibody against human ROR1 and use for the same

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Seongnam-si, South Korea

Kyungjin Park