Samsung Electronics Co., Ltd.

Kyung-hee Park

Yeon-Su Lee

Kyu-sang Lee

Jae-Heup Kim

Myo-yong Lee

Tae-Jin Ahn

Yeon-a Park

Ok-kyoung Son

Ye-ryoung Yong

Hyun-ju Kang

Ga-hee Kim

Dong-hyun Park

Ji-Young Cho

Byung-chul Kim

Min-Sun Kim

Kyusang Lee

Jong-suk Chung

Sung-woo Hong

Jung-joo Hwang

Hyo-jeong Jeon

Ok-ryul Song

Byung-Chul Kim

Jong-myeon Park

Ji-young Oh

Jung-nam Lee

Nam Hwi Hur

Jong-Hoon Park

Ki-eun Kim

Kyu-Sang Lee

Yun-Sun Nam

Sang-hyun Paek

Seung-Hak Choi

Dae-Soon Son

Ah-gi Kim

Kyoung-a Kim

Jhin-gook Kim

Ji-young Cho

Yeon-A Park

Sung-Woo Hong

Jung-Joo Hwang

Hyo-Jeong Jeon

Jae-Heup 2-1307 Daelim Apt Kim

Yeon-A 101-106 Sejong Regencyvill Park

Ok-Kyoung 101-605 Kukdong Apt Son

Min-Sun 403-403 Jugong Apt Kim

Yeon-Su 1003-102 Seongjeo Maeul Kunyoung V Lee

Kyu-Sang 102-1702 Dongsuwon Lg Village 1-Cha Lee

Byung-Chul 102-1202 Woonam Firstvill Kim

Ji-Young 111-1107 Sejong Apt Cho

A breast cancer diagnostic composition and kit, and methods of diagnosing breast cancer or acquiring information for breast cancer diagnosis by using the composition or kit are provided. The composition or kit includes a polynucleotide that is the same as or complementary to at least one microRNA (miRNA) selected from the group consisting of hsa-miR-126, hsa-miR-23a, hsa-miR-24, hsa-miR-19b, hsa-miR-103, hsa-miR-142-3p, hsa-miR-144, hsa-miR-15a, hsa-miR-185, hsa-miR-93, and hsa-miR-30c in a vesicle, or a fragment of the microRNA.

Composition and kit for diagnosing breast cancer including polynucleotide within vesicle, and method of diagnosing breast cancer using the same

Provided is a dual-hybridization polynucleotide including a first complementary region that is complementary to the 3'-terminus of a target nucleic and a second complementary region that is complementary to the 5&#x2032;-terminus of the target nucleic acid, a composition and kit including the polynucleotide, and a method of producing a nucleotide sequence complementary to the target nucleic acid. The first complementary region to be bound at the 3&#x2032;-terminus of the target nucleic acid can be shortened and the target nucleic acid may be amplified with excellent specificity and/or sensitivity.

Polynucleotide and use thereof

Provided is method of diagnosing liver cancer in a subject, the method comprising contacting a sample from a subject with a substance that specifically binds to transmembrane emp24 domain trafficking protein 2 (TMED2), cluster of differentiation 43 (CD43), or any combination thereof on the surface of a microvesicle; and measuring the level of the substance bound to microvesicles in the sample; and related methods and compositions.

Composition for diagnosing liver cancer and methods of diagnosing liver cancer and obtaining information for diagnosing liver cancer

Provided are a method and apparatus for analyzing genotype data plotted in a two-dimensional space. The method includes: connecting points representing the genotype data to a predetermined point to form straight lines and obtaining angles between adjacent straight lines; extracting the two largest angles from the obtained angles; and analyzing the plotted genotype data using three groups of the genotype data separated by the two extracted largest angles. According to the present invention, when the experimental results of classifying genotype are to be analyzed, the two largest angles from the angles obtained by connecting straight lines between points representing each of the genotype data and a predetermined point plotted in a two-dimensional space are detected, and three data regions separated by the detected two largest angles are used to analyze the genotype data. Thus, a large amount of the experimental data for classifying the genotype can be analyzed rapidly and conveniently.

Method and apparatus for analyzing genotype data

Provided are a method of analyzing a sequence of a first probe nucleic acid using a substrate on which a second probe nucleic acid is immobilized, and a microarray and a kit for the same.

Method of analyzing probe nucleic acid, microarray and kit for the same

Provided is a polynucleotide including at least 10 contiguous nucleotides of a nucleotide sequence selected from the group consisting of nucleotide sequences of SEQ ID NOS: 1-12 and including a nucleotide at position 101 of the nucleotide sequence, or a complementary polynucleotide thereof.

Polynucleotide associated with a colon cancer comprising single nucleotide polymorphism, microarray and diagnostic kit comprising the same and method for diagnosing a colon cancer using the polynucleotide

Provided is a polynucleotide for diagnosis or treatment of breast cancer, including at least 10 contiguous nucleotides of a nucleotide sequence selected from the group consisting of nucleotide sequences of SEQ ID No: 1 to SEQ ID No: 5 and comprising a nucleotide at 101position of the nucleotide sequence, or a complementary polynucleotide thereof.

Polynucleotide associated with breast cancer comprising single nucleotide polymorphism, microarray and diagnostic kit comprising the same and method for diagnosing breast cancer using the same

A multiple single nucleotide polymorphism (multi-SNP) marker for cardiovascular disease diagnosis and a method of diagnosing cardiovascular disease are provided. Also, sets of polynucleotides, a microarray, and a kit including the microarray are provided.

Multiple SNP for diagnosing cardiovascular disease, microarray and kit comprising the same, and method of diagnosing cardiovascular disease using the same

An isolated protein having an amino acid sequence of SEQ ID No. 4 and having an activity inducing apoptosis, and a gene encoding the same are provided. Also, a microarray having a substrate on which the gene or fragment thereof is immobilized is provided. Also, a method of diagnosing breast cancer using an antibody specifically binding to the protein and a method of diagnosing breast cancer by determining whether the gene is expressed in a cell or not, are provided.

Breast cancer related protein, gene encoding the same, and method of diagnosing breast cancer using the protein and gene

Provided are a primer set for specifically amplifying target sequence(s) of twelve respiratory disease-causing bacterial species, a probe set specifically hybridizing with target sequence(s) of twelve respiratory disease-causing bacterial species, a microarray comprising the probe set, and a method of detecting a respiratory disease-causing bacterial species using the probe set.

Method and compositions for detecting respiratory disease-causing bacterial species

Provided is a polynucleotide for diagnosis or treatment of type II diabetes mellitus, including at least 10 contiguous nucleotides of a nucleotide sequence selected from the group consisting of nucleotide sequences of SEQ ID NOS: 1-80 and including a nucleotide at position 101 of the nucleotide sequence, or a complementary polynucleotide thereof.

Polynucleotide associated with a type II diabetes mellitus comprising single nucleotide polymorphism, microarray and diagnostic kit comprising the same and method for analyzing polynucleotide using the same

Provided is a method of selecting an optimized SNP marker set from a plurality of SNP markers. The method includes selecting an SNP marker set having a high association from a plurality of SNP markers using set-association, selecting SNP markers having a high association by performing discrimination analysis on arbitrary combinations of the markers included in the SNP marker set, and selecting an optimized SNP marker combination satisfying predetermined selection criteria by using receiver operating characteristics (ROC) curve analysis of arbitrary combinations of the selected SNP markers.

Method of selecting optimized SNP marker sets from multiple SNP markers associated with a complex disease

Provided is a method of predicting risk of lung cancer recurrence in a lung cancer patient or after a patient has lung cancer treatment, the method including: obtaining a biological sample from a lung cancer patient; measuring an expression level of at least one marker gene from the biological sample, the marker gene being selected from the group consisting of marker genes of Table 1, 2 or 3, to obtain data for the expression level of the marker gene; and determining whether the expression level of the marker gene corresponds to an expression level of a recurrence group or an expression level of a non-recurrence group.

Method of predicting risk of lung cancer recurrence, and a composition, kit and microarray for the same

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Seoul, South Korea

Kyung-hee Park