The University of British Columbia

Tapimmune Inc.

Kyung Bok Choi

Wilfred A Jefferies

Reinhard Gabathuler

Franz Fenninger

Brett Alexander Eyford

Lonna Munro

Cheryl Gurine Pfeifer

Shawna Rose Stanwood

Timothy Z Vitalis

Susan Shu-Ping Chen

Quian-Jin Zhang

Judi Barbara Alimonti

Genc Basha

Wilfred Arthur Jefferies

Provided are antibodies, and antigen-binding fragments thereof, which specifically bind to an extracellular poor loop of an alpha 1a subunit of L-type voltage gated calcium channel, and related compositions, kits, and methods of use thereof, for instance, administration to a subject in need thereof to modify an immune response, for example, in the treatment of cancer.

Antibodies to L-type voltage gated channels and related methods

A vaccine composition for combatingviral infections in living organisms such as mammals (including humans) comprises TAP-1 and/or TAP-2 to augment the antigen processing capability of infected cells and hence their immunogenicity. The composition may be used alone or, preferably, as an immunogenicity-enhancing adjuvant with a pox antigen-based vaccine, especially in the treatment or prophylaxis of viral infections such as smallpox.

[object Object]

Growing community of inventors

Vancouver, Canada

Kyung Bok Choi