Lg Chemical Ltd.

Paean Biotechnology Inc.

Paean Aesthetics Inc.

Kyuboem Han

Youngjun Lee

Jongcheon Ha

Sang Yup Lee

Yong-Jun Lee

Junyoung Son

Jong-il Choi

Soon-Jae Park

Hong-Kyun Lee

Hye Jeong Hwang

Se-Hoon Kim

Seung-Joo Lee

Sang-Min Lim

Young-Cheol Kang

Young-Phil Lee

Seong Soo Jeon

Hahnsun Jung

JongCheon Ha

Provided is a composition for injection containing isolated mitochondria. More specifically, provided is a liquid composition for injection containing glycine, saccharide, buffer, and mitochondria, and a pharmaceutical composition comprising the liquid composition for injection as an active ingredient. The liquid composition for injection according to the present disclosure is capable of securing the safety of a mitochondrial therapeutic and maintaining the activity of mitochondria, by enhancing the stability of mitochondria for prevention or treatment of mitochondria-related diseases and preventing and inhibiting formation of blood clots in the blood of a subject who is administered with the same. Accordingly, the pharmaceutical composition according to the present disclosure may solve the aggregation that may occur when mitochondria are administered in the body and thus enables to safely and effectively inject mitochondria into the body to be used for the purpose of preventing and treating various diseases caused by mitochondrial dysfunction.

Injection composition containing isolated mitochondria, and use thereof

An NK cells and PBMC, both having increased cytotoxicity are provided. Particularly, NK cells and PBMC which have exogenous mitochondria introduced thereinto potentiate the immune system of the human body to enhance a therapeutic effect on infectious diseases or cancer. Therefore, the NK cells and PBMC can be used in a composition for prevention or treatment of infectious diseases and cancer. Specially, autogenous NK cells and PBMC guarantee stability without the incurrence of an immune reaction, and thus would be expected to have high commercial activity.

Natural killer cell containing exogenous mitochondrium and pharmaceutical composition comprising same

Disclosed herein are water-soluble microneedle spicules for scrubs and a non-aqueous cosmetic composition containing the same. More specifically, the present invention relates to water-soluble microneedle spicules for scrubs, which are in the shape of a triangular pyramid or sexangular pyramid and characterized in that at least any one among the interior angles of the pyramid base of the spicules for scrubs is 90 degrees or less; and a non-aqueous cosmetic composition containing the same.

Water-soluble microneedle spicules and non-aqueous cosmetic composition containing the same

The present invention relates to a non-aqueous cosmetic composition comprising water-soluble scrub particles containing a polypeptide or a cell culture component. More specifically, the present invention relates to a non-aqueous cosmetic composition comprising 0.01 wt % to 15 wt % of hard and angulated water-soluble scrub particles containing cell culture components or various polypeptides including a peptide and an oligopeptide. Further, the cosmetic composition of the present invention provides a non-aqueous cosmetic composition which does not comprise active ingredients, but comprises water-soluble excipient scrub particles for maintaining or improving a scrubbing effect and adjusting viscosity or volume.

Cosmetic composition including water soluble scrub particles containing polypeptide and/or cell culture

A process for the preparation of biologically active somatotropin from inclusion bodies of a recombinant host cell containing an inactive form of said somatotropin protein comprises the steps of:

Process for the preparation of active somatotropin from inclusion bodies

There are described methods for making polyhydroxyalkanoate and its copolymers, by culturing a host cell transformed with a vector comprising a polyhydroxyalkanoate biosynthesis-related DNA fragment isolated from . The DNA fragment comprises genes that encode for polyhydroxyalkanoate synthase, &bgr;-ketothiolase, and acetoacetyl-CoA reductase.

Methods of making polyhydroxyalkanoate using biosynthesis genes from alcaligenes latus

The present invention relates to a process for removing methionine (Met) residue at N-terminus of proteins specifically. Particularly, the present invention relates to an aminopeptidase which is purified from removes a methionine residue from N-terminus of peptide and proteins. And the present invention relates to a process for preparing a natural type protein from proteins produced in microorganisms by recombinant DNA technology. Various kinds of natural type proteins such as human growth hormone (HGH) can be prepared massively and easily by the process of the present invention.

Aminopeptidase derived from Bacillus licheniformis and process for preparation of natural type proteins

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Daejeon, South Korea

Kyuboem Han