Nof Corporation

Kyu Takeuchi

Midori Hirai

Atsushi Sato

Ryo Kawahara

A method for purifying a branched polyethylene glycol, which includes adding, to a branched polyethylene glycol compound represented by the following formula [1] and having a weight average molecular weight of 40,000 or more: where Z, Y, Y, A, Polymer, l, m and b are as defined herein, at least one solid acid selected from magnesium silicate, aluminum silicate, and aluminum magnesium silicate and having a specific surface area of 50 to 250 m/g in the presence of an aprotic organic solvent to obtain a mixture; stirring the mixture; and subsequently separating the solid acid.

Method for purifying branched polyethylene glycol

A method for purifying a polyethylene glycol compound represented by formula [1], including a Step (A) of dissolving the compound represented by formula [1] in an organic solvent having a Hildebrand solubility parameter of 8 to 10 (cal/cm)to obtain a solution, and a Step (B) of mixing the solution with 0.1 to 1 part by mass of an adsorbent made from a hydrotalcite having a specific surface area of 50 to 200 m/g with respect to 1 part by mass of the compound of the formula [1] to prepare a slurry, where Z, Y, Y, A, Polymer, X, a, b, l and m are as defined herein.

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Kawasaki, Japan

Kyu Takeuchi