Lucky Limited

Inha-Industry Partnership Institute

Kyu B Han

Tae Hee Lee

Yong Bum Lee

Young Woo Park

Joong Myung Cho

Hyun H Chung

David H Sherman

Eung-Soo Kim

Zixin Deng

Linquan Bai

Shuangjun Lin

Dekun Kong

Mi-Jin Lee

Hyeon H Jeong

Jung M Jo

Yeong W Park

The present invention relates to a novel polyene compound similar to nystatin, a method for preparing the same, and an antifungal drug comprising the novel polyene compound as an active ingredient. Compared to nystatin comprising one sugar, NNP, which is the polyene compound similar to nystatin, displays 300 times higher solubility and ten times lower cytotoxicity while maintaining antifungal activity, and thus can be useful in developing a novel polyene antifungal agent having improved solubility and less toxicity in terms of pharmacokinetics.

Polyene compound, method for preparing the same, and antifungal drug comprising novel polyene compound as active ingredient

High protein content feed or synthetic steroides are used to elevate the efficiency of feed and promote pig growth. However, the steroids are not metabolized quickly but remain in the body for a long time and may have a detrimental influence on humans. The invention relates to a method for the production of porcine growth hormone which improves the growth of pigs and the efficiency of feed using a synthetic gene in yeast cells. It has been found that porcine growth hormone may be produced economically and in bulk in yeast by gene manipulation technology.

Method for the production of porcine growth hormone using a synthetic

Plasmids for the high-level expression of bovine growth hormone in yeast and in E. coli are described, as are processes for the production of bovine growth hormone which utilize host cells transformed with the expression vectors.

Method for production of bovine growth hormone using a synthetic gene

High protein content feed or hormonal steroids have been added to fish feed in order to elevate the efficiency of the feed. However, the steroids remain in the fish and may be detrimental to those who eat the fish. The invention relates to a method for the production of salmon growth hormone, which enhances the efficiency of the feed without the above side effects, using a synthetic gene in yeast or E. coli. It has been found that salmon growth hormone may be produced economically and in bulk in yeast or E. coli by gene manipulation technology.

Method for the production of salmon growth hormone using a synthetic gene

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Daejeon, South Korea

Kyu B Han