Korea Research Institute of Bioscience and Biotechnology

Healthbiome

Kyoung Shim Kim

Chul Ho Lee

Jung Hwan Hwang

Yong-Hoon Kim

Kwang Soo Kim

Won Gon Kim

Baek Soo Han

Mi Jin Sohn

Jung-Hyeon Choi

Yun-Jung Seo

Chun Hyung Kim

In-Bok Lee

Dong Hui Choi

Young Mi Kang

Hoe Yune Jung

Yu Jin Kim

Young-Kyoung Ryu

Jung-Ran Noh

Jun Go

Hye-Yeon Park

Jaehun Kim

Young Keun Choi

Jung Ran Noh

Dong Ho Chang

Byoung Chan Kim

The present invention relates to ansp. strain having prophylactic or therapeutic effects on autism spectrum disorders, and use thereof. When the intestinal microorganismsp. strain of the present invention was orally administered to valproic acid (VPA)-induced autism model mice and BTBR autism model mice, the effects of remarkably improving autism spectrum disorders including repetitive behaviors, hyperactivity, social deficiency and cognitive/memory dysfunction of the mice were observed, as compared with a non-treated control. Accordingly, it may be usefully applied to foods, drugs, or feeds for preventing or treating autism spectrum disorders, and thus is very useful in the relevant industries.

Composition for preventing, improving, or treating autism spectrum disorders includingsp. strain as active ingredient

The present invention relates to: a composition comprising aextract or a fraction thereof as an effective ingredient for preventing, alleviating, or treating liver diseases; and a method for preventing or treating liver diseases, comprising a step of administering the composition to a subject suspected of having a liver disease.

Composition for treating or preventing liver diseases, containing sicyos angulatus extract as active ingredient

The present invention relates to a pharmaceutical composition for preventing or treating Parkinson's disease, which comprises, as an active ingredient, aextract obtained by extracting the stem ofwith an organic solvent, and a food additive showing the effect of preventing or treating Parkinson's disease, the food additive comprisingextract as an active ingredient. Theextracts of the present invention may prevent or treat Parkinson's disease without producing any particular side effects, and therefore can be widely used for more safely treating Parkinson's disease.

Composition containing jetbead extracts

The present invention relates to: a pharmaceutical composition or a Nurr1 activating composition for the prevention or treatment of a neurodegenerative disease or a disease induced by impaired Nurr1 function, wherein the composition comprises an active ingredient in the form of genkwanin N or yuanhuacine, aextract comprising one or more of the above compounds, or a fraction thereof; or a functional food additive for preventing or alleviating a neurodegenerative disease or a disease induced by impaired Nurr1 function, wherein the additive comprises genkwanin N or yuanhuacine, aextract comprising one or more of the above compounds, or a fraction thereof; and a method for the prevention or treatment of a neurodegenerative disease or a disease induced by impaired Nurr1 function, wherein the method comprises the step of administering the pharmaceutical composition.

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Daejeon, South Korea

Kyoung Shim Kim