Fujifilm Corporation

Kyosuke Tsumura

Taira Murakami

Jun Nakabayashi

Shino Ohira

Keizo Kimura

Hiroshi Yokoyama

Takumi Nakamura

Akio Mizuno

Mizuki Takei

Keisuke Nogoshi

Ichiro Amasaki

Yukie Watanabe

Kotaro Kudo

Kohei Aizu

Tadao Shibamoto

Provided are a feature quantity calculating method, a feature quantity calculating program, and a feature quantity calculating device which enable calculation of a feature quantity accurately showing chemical properties of a target structure, a screening method, a screening program, and a screening device which enable efficient screening of a pharmaceutical candidate compound using a feature quantity, and a compound creating method, a compound creating program, and a compound creating device which enable efficient creation of a three-dimensional structure of a pharmaceutical candidate compound using a feature quantity. Since the chemical properties of target structures are exhibited as the result of an interaction between the target structure and probes in the periphery thereof, the fact that the degree of accumulation of the probes is similar between target structures indicates that the chemical properties of the target structures are similar. Therefore, the feature quantity accurately showing the chemical properties of the target structure can be calculated using the feature quantity calculating method according to one aspect of the present invention.

Feature quantity calculating method, feature quantity calculating program, and feature quantity calculating device, screening method, screening program, and screening device, compound creating method, compound creating program, and compound creating device

Provided are a method for searching for a molecular stable structure, a program for searching for a molecular stable structure, and a device for searching for a molecular stable structure, which are capable of acquiring a stable structure and various locally stable structures from a structural formula of a compound in a short time and with high accuracy. A three-dimensional structure is generated from the structural formula of the compound, and a locally stable structure is obtained from the three-dimensional structure. A one-dimensional or multidimensional energy distribution function for one or a plurality of internal coordinates and a probability distribution function of increasing a probability of low-energy internal coordinates are calculated from internal coordinates and an energy value of the locally stable structure. The method for searching for a molecular stable structure repeats the following processes: generating a three-dimensional structure based on the calculated probability distribution function; acquiring a locally stable structure; reflecting internal coordinates and an energy value of the obtained locally stable structure on the energy distribution function and the probability distribution function; and acquiring the locally stable structure, thereby obtaining a plurality of the locally stable structures and a structure with lowest energy. The program and the device for searching for a molecular stable structure execute the method.

Method for searching for molecular stable structure, program for searching for molecular stable structure, and device for searching for molecular stable structure

A planographic printing plate precursor includes: a support; and an image recording layer which includes a radical initiator, a radical polymerizable component, and a radiation absorption compound, and in which the image recording layer shows two or more peaks of a radical generation amount in a radical generation amount-versus-time curve after exposure to image forming radiation, in which the radical initiator includes an electron-donating radical initiator and an electron-accepting radical initiator, and the radiation absorption compound comprises a compound represented by the following Formula 1. 

Radiation-sensitive composition, planographic printing plate precursor, and plate-making method for planographic printing plate

A color developing composition which develops colors in a high density and does not significantly discolor when aged, a lithographic printing plate precursor which has excellent plate-inspecting properties by means of color development and is capable of maintaining strong color development even when aged after color development, a plate making method for a lithographic printing plate in which the lithographic printing plate precursor is used, and a new compound that can be preferably used as a color developer. The color developing composition of the present invention includes a compound represented by Formula 1. The compound in the present invention is represented by Formula 1. In Formula 1, Rrepresents a group in which an R&#x2014;O bond is cleaved by heat or exposure to infrared rays. 

Color developing composition, lithographic printing plate precursor, plate making method for lithographic printing plate, and color developer

To provide a novel triazine-based compound exhibiting an ultraviolet blocking effect even in the long-wavelength region and being useful as an ultraviolet absorber with excellent light resistance, and to provide an ultraviolet absorber and a resin composition, which can maintain a long-wavelength ultraviolet-blocking effect for a long period of time. A compound represented by the following formula (1): 

Triazine derivative, ultraviolet absorber, and resin composition

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Shizuoka, Japan

Kyosuke Tsumura