Adeka Corporation

Josho Gakuen Educational Foundation

Kyohei Ochiai

Ken-ichiro Hiwatari

Shinji Sakuma

Kohta Mohri

Naoki Morimoto

Tetsuya Higami

Yu Yamaguchi

Haruki Obara

Kenichiro Hiwatari

Takuya Kimura

Mitsumasa Homma

Keita Kinoshita

A method of producing a decellularized transplantation material, wherein the method includes the steps of (a) harvesting a branch-bearing blood vessel from a vertebrate animal (a donor); (b) decellularizing the blood vessel; and (c) adhering, by a protein denaturation treatment, a portion where a branch has been excised to close the vessel. Also, a graft composition consisting of a biocompatible material that contains the decellularized transplantation material.

Method for producing decellularized material for transplantation and graft composition consisting of biocompatible material including said material

A polysaccharide derivative has a partial structure represented by Formula (1) below. It is preferable that at least one of the amino acids that constitute Xin Formula (1) below is a basic amino acid. 

Polysaccharide derivative having membrane-permeable peptide chain

A polymer compound has a group represented by Formula (1) or Formula (2) in a side chain. (In Formula (1), Xrepresents a neutral amino acid residue or an &#x3c9;-aminoalkanoic acid residue, Xrepresents a membrane-permeable peptide residue, Xrepresents a hydroxyl group, an amino group, an alkoxyl group having 1 to 4 carbon atoms, or a benzyloxy group, and a represents a number of from 1 to 50.) (In Formula (2), Xrepresents a neutral amino acid residue or an &#x3c9;-aminoalkanoic acid residue, Xrepresents a membrane-permeable peptide residue, Xrepresents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a benzyl group, an acyl group having 1 to 6 carbon atoms, an arylsulfonyl group, or a carboxyl group, and b represents a number of from 1 to 50.).

Polymer compound which has membrane-permeable peptide in side chain

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Kyohei Ochiai