W. L. Gore & Associates, Inc.

Edwards Lifesciences Corporation

Kyle W Colavito

Cody L Hartman

Dustin V Dienno

Nathan L Bennett

Edwin W Field

Joseph R Armstrong

Roy Manygoats, Jr

Joshua A Sprinkle

David J Arcaro

David M Warlop

James L Goepfrich

Paul D Goodman

Brandon A Lurie

Ryan S Titone

Logan R Hagaman

Brandon C Hedberg

Michael J Shepard

Benjamin A Smith

Devin M Nelson

Benjamin D Campbell

Ryan D Smith

Colin T Burns-Heffner

Sudeep Sastry

Karl Busalacchi

Carl M Conway

Vi T Pham

Roy Manygoats

Marc A Schlaud

Frank E Myers

Steven Cureton

Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a valved conduit. The valved conduit may include at least one leaflet and an interior surface that mitigates against thrombus formation within the conduit.

Valved conduit

Described embodiments are directed toward centrally-opening leaflet prosthetic valve devices having synthetic leaflets that are configured to promote and encourage tissue ingrowth thereon and/or therein. The leaflets are coupled to a leaflet frame to form a prosthetic valve suitable for use in biological anatomy.

Medical valve and leaflet promoting tissue ingrowth

Described embodiments are directed toward prosthetic valves having a support structure and at least one leaflet. The leaflet comprises means for allowing fluid that is behind the leaflet to pass through to the front of the leaflet when the leaflet is not in the closed position. The prosthetic valve includes a leaflet moveable between an open position that permits antegrade flow through the prosthetic valve and a closed position that prevents regurgitant flow through the prosthetic valve, the leaflet having an aperture or gap, or a separation of portions of the leaflet to allow a flow or exchange of fluid between a front and back of the leaflet, when the leaflet is not in the closed position.

Prosthetic valve with improved washout

Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that include a prosthetic valve. The prosthetic valve may include a jacket configured to cover at least one of gaps, spaces, or interfaces in a frame or between one or more leaflets attached to the frame.

Jacket for surgical heart valve

Prosthetic valved conduits are provided that include a leaflet construct coupled between two portions of a conduit. Each leaflet has a free edge and a leaflet attachment edge. The leaflet attachment edge is disposed between a first conduit distal end and a second conduit proximal end that are coaxial therebetween defining a junction.

Prosthetic valved conduit

Various features and associated advantages are described for diametrically adjustable support structures, adjustable valve structures, removable/replaceable valve structures, and associated systems and methods. Although some examples are directed toward prosthetic valve that is a conduit having a valve structure, or a 'valved conduit' (e.g., used to replace a pulmonary valve and a portion of the corresponding pulmonary artery or an aortic valve and the aortic root), and other examples are directed toward prosthetic valves implanted native valve orifices (e.g., to replace an aortic or mitral valve), the features and advantages of the structures associated with those examples are interchangeable regardless of a particular application for which the examples are described.

Diametric expansion features for prosthetic valves

Pulmonary valve conduit

Valved conduits are provided that include a leaflet construct coupled between two portions of a conduit. Each leaflet has a free edge and a leaflet attachment edge. The leaflet attachment edge is disposed between a first conduit distal end and a second conduit proximal end that are coaxial therebetween defining a junction.

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Flagstaff, AZ, United States of America

Kyle W Colavito