James Madison Innovations, Inc.

University of Florida Research Foundation Inc

University of Utah Research Foundation

St. Jude Children's Research Hospital

Kyle Seifert

Kevin L Caran

John Bohnsack

Elisabeth Adderson

Kevin Patrick Minbiole

Ronald W Raab

Robert L McKown

Linda Jeannine Brady

The inventive subject matter relates to novel antibodies to lacritin splice variants, improved methods for detecting lacritin splice variants, and methods for diagnosing Sj&#xf6;gren's Syndrome.

Methods and reagents for diagnosing Sj&#xf6;gren's Syndrome

The inventive subject matter relates to compounds of Formula I and Formula II, compositions thereof, and processes for making such compounds as presently claimed and further described herein. The inventive compounds and compositions have antimicrobial properties and are useful as environmental disinfectants, topical cleansers such as topical personal care compositions, sanitizers, preservatives, in water treatment, as permanent or erodible coatings for medical devices and appliances, and in therapeutics.

Triscationic amphiphile compounds, compositions, and methods for making same

The inventive subject matter relates to compounds of Formula I, compositions thereof, and processes for making such compounds as further described herein. The inventive compounds and compositions have antimicrobial properties and are useful as environmental disinfectants, topical cleansers such as topical personal care compositions, sanitizers, preservatives, in water treatment, as permanent or erodible coatings for medical devices and appliances, and in therapeutics. Additionally, the compounds of Formula I will serve as synthetic intermediates for making additional novel derivatives of triscationic amphiphile compounds.

Triscationic amphiphile derivative compounds having a pendent alcohol group, compositions thereof, and methods for making same

The present invention is directed to compositions useful for antimicrobial applications. These compositions comprise amphiphilic compounds.

Antimicrobial amphiphiles and methods for their use

The present invention provides a group B(GBS) surface antigen, designated epsilon antigen, that is co-expressed with the delta antigen on a subset of serotype III GBS. Epsilon is expressed on more pathogenic Restriction Digest Pattern (RDP) III-3 GBS, but not on RDP types 1, 2, or 4. Accordingly, the present invention provides compositions and methods for detecting a group Bserotype III, RDP III-3 strain. Vaccines and methods of identifying agents which inhibit adhesion of a group Bcell to a host cell are also provided.

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Harrisonburg, VA, United States of America

Kyle Seifert