E.i. Dupont De Nemours and Company

Alliance for Sustainable Energy, LLC

Kyle Knoke

Perry G Caimi

Luan Tao

Paul Veikko Viitanen

Min Zhang

Yat-Chen Chou

Mary Ann Franden

Yuying Zhang

Through screening of amutant library the himA gene was found to be involved in the inhibitory effect of acetate onperformance. Xylose-utilizingstrains further engineered to reduce activity of the himA gene were found to have increased ethanol production in comparison to a parental strain, when cultured in mixed-sugars medium comprising xylose, and, in particular, in the presence of acetate.

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Through screening of amutant library the himA gene was found to be involved in the inhibitory effect of acetate onperformance. Xylose-utilizingfurther engineered to reduce activity of the himA gene were found to have increased ethanol production in comparison to a parental strain, when cultured in medium comprising xylose and acetate.

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Newark, DE, United States of America

Kyle Knoke