3m Innovative Properties Company

Minnesota Mining and Manufacturing Company

Coley Pharmaceutical Group, Inc.

Graceway Pharmaceuticals, LLC

Other

Kyle J Lindstrom

Bryon A Merrill

John F Gerster

Michael J Rice

Philip D Heppner

Stephen L Crooks

Gregory J Marszalek

John W Mickelson

Chad A Haraldson

Joseph F Dellaria, Jr

Tushar A Kshirsagar

Bryan V Hunt

George W Griesgraber

Shri Niwas

Peter V Maye

Joshua R Wurst

Anthony M Renstrom

Luke T Dressel

David B Olson

Matthew R Radmer

Judith M Invie

Nick Nikolaides

Patrick L Coleman

Doris Stoermer

Scott E Langer

Gregory D Lundquist, Jr

Sarah J Slania

John R Jacobsen

David S Hays

William H Moser

Michael E Danielson

Joan T Moseman

Karl J Manske

Maureen C Nelson

Hugues M H Martin

Stephen A Johnson

Richard G Hansen

Robert A Yapel

Christopher Bland Walker, Jr

Tri Dinh Pham

Clinton L Jones

James P DiZio

Maureen Ann Kavanagh

David T Amos

Sarah A Strong

Steven H Kong

Taun L McKenzie

Mitchell A F Johnson

Michelle Lund Toy

Bernhard M Zimmermann

Joseph T Aronson

Daniel E Duffy

Benjamin J Bending

Byron A Merrill

Christopher P Tebow

Michael K Gerlach

Sarah C Johannessen

Sarah C Slania

Sarah Johannessen

David J Squire

Hugues Martin

Presently described are optical films comprising a polymerized (e.g. microstructured) surface that comprises the reaction product of a polymerizable resin composition and polymerizable resin compositions that comprise nanoparticles; at least one first monomer comprising at least two (meth)acrylate groups; and at least one second (meth)acrylate monomer having the structure

Benzyl (meth)acrylate monomers suitable for microstructured optical films

Optical films are described having a polymerized microstructured surface that comprises the reaction product of a polymerizable resin composition comprising at least one polymerizable ethylenically unsaturated triphenyl monomer. Also described are certain triphenyl (meth)acrylate monomers and polymerizable resin compositions.

Triphenyl monomers suitable for microstructured optical films

Presently described are optical films comprising a polymerized (e.g. microstructured) surface that comprises the reaction product of a polymerizable resin composition and polymerizable resin compositions that comprise nanoparticles; at least one first monomer comprising at least two (meth)acrylate groups; and at least one second (meth)acrylate monomer having following the structure (I); wherein at least one R1 comprises an aromatic substituent, t is an integer from 1 to 4, and R2 is hydrogen or methyl. 

Imidazoquinoline compounds with an alkoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.

Alkoxy substituted imidazoquinolines

The present invention concerns antireflective films comprising a high refractive index layer () and low refractive index layer () disposed on the high refractive index layer. The antireflective films have a microstructured surface () that can be derived from a microreplicated tool.

Antireflective films comprising microstructured surface

Optical films are described having a polymerized microstructured surface that is the reaction product of a polymerizable resin composition comprising at least one polymerizable ethylenically unsaturated triphenyl monomer. Also described are certain triphenyl (meth)acrylate monomers and polymerizable resin compositions.

A method of making optical films having a polymerized microstructured surface are described. The polymerized microstructured surface comprises the reaction product of a polymerizable resin composition comprising 10% to 100 wt-% of at least one biphenyl di(meth)acrylate monomer. The di(meth)acrylate monomer comprises a core biphenyl structure having two aromatic rings connected with a C&#x2014;C bond. The biphenyl di(meth)acrylate monomer preferably comprises a sufficient amount of ortho and/or meta(meth)acrylate substituents such that the monomer is a liquid at 25&#xb0; C.

Methods of making microstructured optical films comprising biphenyl difunctional monomers

Optical films are described having a polymerized microstructured surface that comprises the reaction product of a polymerizable resin composition comprising at least one polymerizable ethylenically unsaturated triphenyl monomer. Also described are certain triphenyl(meth)acrylate monomers and polymerizable resin compositions.

A method of preferentially inducing IFN-&#x3b1; biosynthesis in an animal comprising administering certain imidazo[4,5-c] ring compounds with a hydroxymethyl or hydroxyethyl substituent at the 2-position or pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of using these compounds a immunomodulators for treatment of diseases including viral and neoplastic diseases comprising preferentially inducing IFN-&#x3b1; biosynthesis in an animal are disclosed.

Method of preferentially inducing the biosynthesis of interferon

Certain imidazonaphthyridines with a hydroxymethyl or hydroxyethyl substituent at the 2-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for preferentially inducing IFN-&#x3b1; biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

Hydroxyalkyl substituted imidazonaphthyridines

Imidazoquinoline compounds with an aryloxy or arylalkyleneoxy substituent at the 6, 7, 8, or 9-position, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for modulating cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.

Aryloxy and arylalkyleneoxy substituted imidazoquinolines

Certain imidazoquinolines with a hydroxymethyl or hydroxyethyl substituent at the 2-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for preferentially inducing IFN-&#x3b1; biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

Hydroxyalkyl substituted imidazoquinolines

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Houlton, WI, United States of America

Kyle J Lindstrom