Boston Scientific Neuromodulation Corporation

Boston Scientific Scimed, Inc.

Kyle Harish Srivastava

Bryan Allen Clark

Elizabeth Mary Annoni

Pramodsingh Hirasingh Thakur

Jianwen Gu

David J Ternes

David L Perschbacher

James John Kleinedler

Rosana Esteller

Sandra Nagale

Jonathan Bennett Shute

Dat Thanh Huynh

Vijay Koya

Dennis Zottola

Dennis A Boismier

Felix Landaeta

Paige V Tracy

Christopher Piere

Tina Marie Lenneman

Kevin J Goodwin

Jeffrey E Stahmann

Gregory J Sherwood

Stephen B Ruble

Bradley Lawrence Hershey

Matthew Lee McDonald

Brian P Watschke

Mark W Boden

Paul F Chouinard

George Wilfred Duval

Craig Michael Stolen

Michael X Govea

Niraj Prasad Rauniyar

Justin Theodore Nelson

William Conrad Stoffregen

Martin Phelan

Mark Kringle

Thomas Lee Williams

Amarpreet Singh Bains

Jason Kilvington

Carl Walter Bauer

Benjamin Phillip Hahn

Nicholas Barron

Miles Kealy

Jason A Kilvington

This document discusses systems, devices, and methods for computer-assisted pain or paresthesia assessment and pain management in a subject. A system includes a programming aid device including a user interface, a transceiver circuit to receive information about pain management for the patient from one or more of a software-based virtual agent (SVA) or a human assistant other than the patient, and a controller circuit to initiate and manage information exchange session between the patient and one or more of the SVA or the human assistant, via the user interface, regarding pain or paresthesia sensation and pain management. Based on the information exchange, the controller determines a stimulation setting, and generate a therapy control signal to the neuromodulation device to initiate delivery of neuromodulation energy according to the determined stimulation setting.

Computer-assisted pain mapping and neuromodulation system

This document discusses, among other things, systems and methods for managing pain in a patient. A system may include sensors to sense physiological or functional signals, and a pain analyzer that generates a pain score using the sensed physiological or functional signals and a fusion model. The system includes a calibration module that calibrates the fusion model based on measurements from the sensed physiological or functional signals and a reference pain quantification corresponding to multiple pain intensities. A pain score may be generated using the calibrated fusion model. The system can additionally include a neurostimulator that controls the delivery of pain therapy by adjusting one or more stimulation parameters based on the pain score.

Patient-specific calibration of pain quantification

This document discusses, among other things, systems and methods for managing pain in a subject. A system may include one or more sensors configured to sense from the subject information corresponding to emotional reaction to pain, such as emotional expression. The emotional expression includes facial or vocal expression. A pain analyzer circuit may generate a pain score using signal metrics of facial or vocal expression extracted from the sensed information. The pain score may be output to a user or a process. The system may additionally include a neurostimulator that can adaptively control the delivery of pain therapy by automatically adjusting stimulation parameters based on the pain score.

Pain management based on emotional expression measurements

Example ultrasound medical devices are disclosed. An example medical device includes a support member having a proximal end region and a distal end region and a sensing member having a proximal end region and a distal end region, the distal end region of the sensing member coupled to the distal end region of the support member. The medical device also includes one or more ultrasound sensors disposed along the sensing member and a support shaft having a first end coupled to the sensing member and a second end coupled to the support member. Additionally, the sensing member is configured to shift from a first configuration in which the sensing member is adjacent to the support member to a second configuration in which at least a portion of the sensing member extends away from the support member.

Ultrasound device

A navigation-assisting flexible elongate member, a navigation-assisting system, and a navigation-assisting method for use in navigating within a body to a treatment site. A navigation-assisting sensor, such as an optic fiber, an inductive sensor, a piezoelectric sensor, or a camera, is provided within the wall of the flexible elongate member, so as not to occupy space within a working channel defined by and through the flexible elongate member. When the distal end of the flexible elongate encounters an obstacle/another object (e.g., body tissue or a lumen wall), the navigation-assisting sensor generates a signal indicative of such encounter. Such signal is converted into information (such as by a control unit) usable to navigate the flexible elongate member away from the obstacle and on course to the treatment site.

Devices and systems for an endoscopic procedure

A virtual or augmented reality system is disclosed which is capable of both (i) evaluating prospective implantable neurostimulator patient candidates, and (ii) determining optimal stimulation settings for already-implanted neurostimulation patients. Physiological sensors are included with the system to provide objective measurements relevant to a patient's symptoms, such as pain in a Spinal Cord Stimulation (SCS) system. Such objective measurements are determined during the presentation of various virtual or augmented environments, and can be useful to determining which patients are suitable candidates to consider for implantation. Stimulation settings for already-implanted patients may be adjusted while presenting a virtual or augmented environment to the patient, with objective measurements being determined for each stimulation setting. Such objective measurements can then be used to determine optimal stimulation settings for the patient.

Augmented and virtual reality for use with neuromodulation therapy

This document discusses, among other things, systems and methods for managing pain of a subject. A system includes a first sensor circuit to sense a first signal indicative of a functional state of the subject, a second sensor circuit to sense a second signal different from the first signal, and a controller circuit. The controller circuit may determine an operating mode of the second sensor circuit according to the sensed first signal, trigger the second senor circuit to sense the second signal under the determined operating mode, and generate a pain score using at least the second signal sensed under the determined operating mode. The pain score may be output to a patient or used for closed-loop control of a pain therapy.

Sensor-based pain management systems and methods

Embodiments herein relate to medical devices and methods for using the same to treat cancerous tumors within a bodily tissue. A medical device system herein can include an electric field generating circuit configured to generate one or more electric fields, and control circuitry. The system can include one or more electrodes disposed on a first stimulation lead to deliver the electric fields to a site of a cancerous tumor within a patient and one or more electrodes disposed on a second stimulation lead to deliver the electric fields to the site of a cancerous tumor within a patient. The first and second stimulation leads can be configured to be implanted on or about a duodenum. The electric field generating circuit can generate electric fields at frequencies selected from a range of between 10 kHz to 1 MHz. Other embodiments are also included herein.

Systems and methods for treatment of pancreatic cancer

This document discusses, among other things, systems and methods for managing pain of a subject. A system includes one or more physiological sensors configured to sense a physiological signal indicative of patient brain activity. The physiological signals may include an electroencephalography signal, a magnetoencephalography signal, or a brain-evoked potential. The system may extract from the brain activity signal one or more signal metrics indicative of strength or pattern of brain electromagnetic activity associated with pain, and generate a pain score using the one or more signal metrics. The pain score can be output to a patient or a process. The system may select an electrode configuration for pain-relief electrostimulation based on the pain score, and deliver a closed-loop pain therapy according to the selected electrode configuration.

Pain management based on brain activity monitoring

An example of a system for managing pain may include a pain monitoring circuit, a pain relief device, and a control circuit. The pain monitoring circuit may include a parameter analyzer and a pain score generator. The parameter analyzer may be configured to receive and analyze at least two parameters selected from a physiological parameter indicative of a physiological function or state of a patient, a functional parameter indicative of a physical activity or state of the patient, or a patient parameter including subjective information provided by the patient. The pain score generator may be configured to compute a composite pain score using an outcome of the analysis. The composite pain score may indicate a degree of the pain. The pain relief device may be configured to deliver a pain-relief therapy. The control circuit may be configured to control the delivery of the pain-relief therapy using the composite pain score.

Method and apparatus for pain management using objective pain measure

An Example of a system for providing a patient with pain management may include a sleep monitoring circuit, a pain relief device, and a control circuit. The sleep monitoring circuit may be configured to sense one or more sleep signals from the patient and to determine a sleep state of the patient using the one or more sleep signals. The one or more sleep signals may include one or more physiological signals corresponding to the sleep state of the patient. The pain relief device may be configured to deliver one or more pain relief therapies. The control circuit may be configured to control the delivery of the one or more pain relief therapies using therapy parameters and to adjust the therapy parameters based on the determined sleep state.

Method and apparatus for pain management with sleep detection

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Saint Paul, MN, United States of America

Kyle Harish Srivastava