Life Technologies Corporation

Life Technologies Holdings Pte Limited

Kyle Bulloch

Xin Mathers

Thomas Diller

Joshua Mead

Michael Thacker

Wei Fuh Teo

Neil Olson

Marie Murakami

Ross Winnick

Sandro David Klein

Espir Kahatt

Josh Mead

John Dominic Jackson

Systems are provided for gel electrophoresis and electrotransfer that comprise one or more chambers that can removably and interchangeably receive either an electrophoresis cassette, or an electrotransfer cassette, and provide an electrical interface for both electrophoresis and electrotransfer of biomolecules. Electrophoresis devices including clamps and electrotransfer cassettes and related devices are provided. Methods for electrophoresis and electrotransfer using the systems and devices are also provided.

Electrophoresis and electrotransfer devices, systems, and methods

Electrophoresis and electrotransfer device

Electrophoresis gel cassette

Cassette clamp for electrophoresis gel casting

Electrophoresis slab gel sample loading guide

Electrophoresis cassette and sample loading guide

Cassette support base for electrophoresis gel casting

Western blot processing device housing

An apparatus for preparation of an electrophoresis slab gel may include a base having an opening configured to receive a cassette configured to contain an electrophoresis slab gel, a clamping mechanism configured to move relative to the base between an open position in which the clamping mechanism permits insertion of a cassette into the base, and a closed position in which the clamping mechanism is configured to clamp a cassette received in the base, a compressible pad operatively coupled to the clamping mechanism in a position to compress against a cassette received in the base in the closed position of the clamping mechanism. The cassette may include a first plate and a second plate, and a spacer mechanism separate from each of the first and second plates, the spacer mechanism configured to be positioned between the inner faces of the first plate and the second plate. When subjected to a clamping force exerted on the outer faces of the first and second plates, the spacer mechanism is configured to maintain a separation distance between the inner faces of the first and second plates, and provide a seal to prevent leakage of an electrophoresis gel solution introduced between the plates.

Preparation of electrophoresis gels, and related devices, systems, and methods

Electrophoresis cassette with sample loading guide

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San Diego, CA, United States of America

Kyle Bulloch