Postech Academy-industry Foundation

Kyeng-Min Park

Kimoon Kim

Narayanan Selvapalam

Kangkyun Baek

Erumaipatty Rajagounder Nagarajan

Ilha Hwang

Young-Ho Ko

Jeeyoun Kim

Provided are a stationary phase and a column using a cucurbituril-bound silica gel, and a method of separating taxane using the column. The taxane separation method includes: preparing a column for taxane separation, the column being packed with a stationary phase including a cucurbituril-bound silica gel in which a cucurbituril represented by Formula 1 or 2 is covalently bound to a modified silica gel represented by Formula 3; dissolving a taxane powder in a solvent to prepare a taxane-containing solution; applying the taxane-containing solution to the column; supplying a mobile-phase solvent to the column to obtain a taxane extract from the column; and purifying taxane from the taxane extract. Therefore, highly purified taxane can be separated from a low-purity crude taxane extract.

Stationary phase and column using cucurbituril bonded silica gel, and separation method of taxol using the column

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Pohang, South Korea

Kyeng-Min Park