Hk Inno.n Corporation

Cj Corporation

Cj Cheiljedang Corporation

Cj Healthcare Corporation

Hyundai Motor Company

Kwang Do Choi

Eun Sun Kim

Sung Ah Lee

Min Kyoung Lee

Jae Hong Kweon

Yong Sik Youn

Dong Kwon Lim

Dong Hyun Ko

Chang Ju Kim

Hyuk Woo Lee

Hea Ran Suh

Eun Young Yang

Jae Sun Kim

Hyung Chul Yoo

Jae Kyoung Ko

Ji Yun Lee

SeungPyeong Heo

Chae Young Ryu

Seung Woo Lee

In Woong Lyo

Young Ju Kim

Hong Kil Baek

Woong Pyo Hong

Bokyung Kim

Il Hwan Cho

Jee Woong Lim

Jiyoun Seo

Kwang Hyeg Lee

Seung Chan Heo

Young Joon Park

Seog Beom Song

Myeong Sik Yoon

Yong Tack Lee

Jin Wan Kim

Da Won Oh

Sang Ho Lee

Si Beum Lee

Seong Cheol Bang

Hye Suk Hong

Seungpyeong Heo

Seung Pyeong Heo

The present invention relates to a pidolate salt and malate salt of a compound represented by a formula 1 with an excellent liquid-phase stability, solid-phase stability, water solubility, precipitation stability and hygroscopicity all together as a compound for preventing and treating diseases mediated by an acid pump antagonistic activity, as well as a method for preparing the same.

Acid addition salts of benzimidazole derivative

A preparation method according to the present invention makes it possible to industrially produce large amounts of highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield by use of commercially available reagents and solvents. In addition, the use of novel intermediates according to the present invention makes it possible to produce highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield.

Intermediates for optically active piperidine derivatives and preparation methods thereof

Disclosed is a thermal insulation coating composition including: a polymer resin; an aerogel; and an amphiphilic compound including specific functional groups and having a weight average molecular weight of about 200 to about 5000. A thermal insulation coating layer obtained from the thermal insulation coating composition is also provided.

Thermal insulation coating composition and thermal insulation coating layer

The present invention relates to a novel crystalline form of a benzimidazole derivative and a preparation method thereof. The novel crystalline form according to the present invention is hardly changed chemically and/or physically under a long-term photo-stressed condition, has a low hygroscopicity, and has an extremely low static-electricity-inducing capability, thus being advantageous for formulation, and due to the excellent stability of the crystal form itself, it is very useful for long-term storage of the compound.

Crystalline form of a benzimidazole derivative and a preparation method thereof

The present invention provides a method for preparing a compound with a benzimidazole structure with an excellent yield using a low-cost starting material, not requiring an additional separation process, or not using a dangerous reagent during the manufacturing process. Furthermore, the present invention also provides an intermediate and a final product produced by the preparing method.

Method for preparation of benzimidazole derivatives

The present invention relates to an improved method of preparing adefovir dipivoxil of Formula 1. The method of the present invention is characterized by using dimethylsulfoxide as a reaction solvent, and comprises a process of preparing adefovir dipivoxil of Formula 1 by allowing adefovir of Formula 2 to react with chloromethylpivalate at a reaction temperature of 30 to 50&#xb0; C. under the presence of dimethylsulfoxide and triethylamine solvents. 

Production method for adefovir dipivoxil

Disclosed are novel inorganic acid salts of sibutramine, which have good physicochemical properties, and crystalline forms thereof. Also disclosed are pharmaceutical compositions comprising the compounds as effective ingredients, methods of preparing the compounds, and the use of the compounds.

Inorganic acid salts of sibutramine

Disclosed is a novel sulphonic acid salt of sibutramine, which has good physicochemical properties. Also disclosed are a method of preparing the compound and a pharmaceutical composition comprising the compound.

Sulphonic acid salt of sibutramine

Disclosed is a novel dicarboxylic acid salt of sibutramine, which has good physicochemical properties. Also disclosed are a method of preparing the compound and a pharmaceutical composition comprising the compound.

Dicarboxylic acid salt of sibutramine

Provided is a method for preparing oltipraz. The method includes reacting methyl 2-methyl-3-(pyrazin-2-yl)-3oxopropionate with phosphorus pentasulfide in the presence of a mixed solvent of toluene and xylene, followed by recrystallization.

Method for preparing oltipraz

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Gyeonggi-do, South Korea

Kwang Do Choi