Johnpro Biotech Inc.

Other

Kwan-Hwa Chi

Yu-Shan Wang

Chao-Chun Chang

Hsin-Chien Chiang

Yi-Chun Huang

Kai-Chung Cheng

Disclosed herein are compositions and methods for the treatment of conditions induced by chronic inflammation. According to some embodiments, the compositions and methods involve the use of metformin and sodium butyrate in the treatment of conditions induced by chronic inflammation.

Use of metformin and sodium butyrate for treating conditions induced by chronic inflammation

Disclosed herein are uses of a mammalian target of rapamycin (mTOR) inhibitor and chloroquine or analogue thereof in the manufacture of a medicament for treating cancer patients who are not responsive to a hormone therapy and an immunotherapy. In particular, the medicament is used during the hormone therapy and the immunotherapy to sensitize the patients to the hormone therapy and the immunotherapy.

Use of mTOR inhibitor and chloroquine for treating cancer

A method for using metformin and sodium butyrate in combination to treat a cancer patient with K-ras mutation is disclosed. When administering the pharmaceutical composition to a cancer patient, Metformin and sodium butyrate offer cooperatively therapeutic efficacy. The present invention also discloses a pharmaceutical composition and a pharmaceutical kit containing both aforementioned. The application of the method, the pharmaceutical composition and the pharmaceutical kit of the present invention are advantageous for improving the treatment effect to cancer patients with K-ras mutation.

Method for applying metformin and sodium butyrate in K-ras mutation cancer treatment

Pharmaceutical composition and kit for applying metformin and sodium butyrate in Kras mutation cancer treatment

Growing community of inventors

Taipei, Taiwan

Kwan-Hwa Chi