Basf Aktiengesellschaft

Abbott Gmbh & Co Kg

Kurt Schellhaas

Gerd Steiner

Liliane Unger

Wilfried Hornberger

Wilfried Lubisch

Andreas Kling

Udo Lange

Helmut Mack

Karsten M Wicke

Achim Moeller

Dorothea Starck

Martin Schmidt

Reinhold Mueller

Franz Emling

Monika Knopp

Laszlo Szabo

Hans-Peter Hofmann

Francisco Javier Garcia-Ladona

Uta Holzenkamp

Margaretha Bakker

3-Substituted 3,4-dihydrothieno[2,3-d]pyrimidin-4-one derivatives, production and use thereof. The invention relates to 3,4-dihydrothieno[2,3-d]pyrimidin-4-one derivatives which are substituted in position 3 by 5-membered heteroaryl which may be fused to an aryl or heteroaryl radical, where the heteroaryl and, if appropriate, the fused aryl or heteroaryl radical may have 1, 2 or 3 substituents selected independently of one another from C-alkyl, C-alkoxy, C-alkylthio, halogen, CN, halo-C-alkyl, halo-C-alkoxy, hydroxy, &#x2014;NH, &#x2014;N(R6), &#x2014;NH(R6), aryl, aryloxy, aralkyl, aralkyloxy and heteroaryl, where the substituents aryl, aryloxy, aralkyl, aralkyloxy and heteroaryl may have 1, 2 or 3 substituents selected independently of one another from C-alkyl, C-alkoxy, C-alkylthio, halogen, CN, halo-C-alkyl, halo-C-alkoxy, hydroxy, &#x2014;NH, &#x2014;N(R6)and &#x2014;NH(R6). The preparation and use of these derivatives, especially for therapeutic purposes, e.g. for the treatment of depressions, are likewise described.

3-Substituted 3,4-dihydro-thieno[2,3-d]pyrimidin-4-one derivatives, production and use thereof

Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia

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Ludwigshafen, Germany

Kurt Schellhaas