Aderans Research Institute, Inc.

Johnson & Johnson Consumer Companies, Inc.

Johnson & Johnson Consumer Products, Inc.

Kurt S Stenn

Xunwei Wu

Larry Scott, Jr

Daniel J Hussey

Stephen J Wisniewski

Jonas C T Wang

Susan M Niemiec

Satish Parimoo

Gwang Wei Lu

John DePiano

Gary F Prokop

Martin Rathgeber

Robert J Verdicchio

Morris Yang

Stephen M Prouty

Stephen A Cochran

Terrell A Pruitt

Bryan T Marshall

Yandong Su

Ying Zheng

Kenneth Justin Washenik

Samuel E Carasso

Jose R Pardinas

Nicholas Combates

Compositions and methods for producing reconstituted human skin and/or hair follicles in situ are provided. The method for producing the skin is unique in that tissue culture expanded cells including multipotent cells such as neonatal cells as well as cultured epidermal and dermal cells are immediately placed on a substrate such as a membrane and then the membrane with adherent cells is placed on a skin wound. Examples demonstrate formation of hair follicles in situ.

Compositions and methods for producing reconstituted skin

The present invention provides a method for determining hair inductive properties of a composition comprising injecting a composition comprising dissociated dermal cells and epidermal cells into skin of a mammal and determining whether at least one hair follicle forms.

Methods for determining the hair follicle inductive properties of a composition

The present invention provides fluid and material delivery methods and devices for practicing the methods. The invention provides a method of delivering cellular material comprising injecting the cellular material into a subject such that the injected cells retain their inherent morphologic characteristics upon injection. The method comprises the steps of aspirating the cellular material into a fluid delivery device which incorporates a syringe arrangement. The cellular material is aspirated into the main body of the syringe until the desired amount of a material has filled the syringe body. The needle of the fluid delivery device is then inserted into the skin of a subject at an angle about parallel to the skin until a desired depth has been reached. The cellular material is then injected in the subject until the desired volume of material has been injected. The needle of the device is then rotated approximately 45 to 90 degrees and the needle is removed from the injection site.

Apparatus and methods for delivering fluid and material to a subject

This invention relates to a method for enhancing the transmembrane penetration of benefit agents using a certain non-ionic lipid/surfactant-containing formulation as an enhancing agent, and the compositions used therein. Various active agents, such as anti-dandruff agents, hair growth agents, hair inhibitor agents, anti-acne agents, anti-aging agents, depilatory agents, and depigmentation agents, may be effectively delivered into the skin, hair follicles and sebaceous glands using the compositions of the present invention.

Topical delivery systems for active agents

This invention relates to pouch or pledget delivery system having an apertured film or fabric covering which assists in evenly and safely distributing topical medicaments.

Tricot-like pouch for the delivery of topical drugs and cosmetics

The method of this invention relates to the use of improved anchor primers and a novel purification process to increase the efficiency and accuracy of the differential display technique.

Technique for differential display

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Princeton, NJ, United States of America

Kurt S Stenn