Degussa Aktiengesellschaft

Kurt Klostermann

Axel Kleemann

Wolfgang Leuchtenberger

Michael Karrenbauer

Rudi E Moerck

L-amino acids present in cleavage solutions obtained in the acylase-catalyzed cleavage of N-acetyl-D,L-amino acids are isolated by use of a strongly acidic ion exchanger in H+ form. First, the mother liquor from a previous treatment cycle is fed to the ion exchanger, and then the cleavage solution and finally the wash water and the discharge from the ion exchanger which is pH-controlled is analyzed into an 'effluent water fraction', an 'N-acetyl-D-amino acid fraction' and an 'L-amino acid fraction'. The last fraction is adjusted by addition of fresh cleavage solution to a pH of between 4.0 and 6.0, and from the mixture which is thus obtained the L-amino acid is isolated by crystallization. The mother liquor which is obtained is recycled back into a subsequent treatment cycle.

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Goldbach, Germany

Kurt Klostermann