Genedit, Inc.

University of California

Kunwoo Lee

Niren Murthy

Dorian Liepmann

Kiana Aran

Irina M Conboy

Michael J Conboy

Jacobo Paredes

Hunghao Chu

Santanu Maity

Provided is a polymer comprising a structure of Formula (1): (1) and a method of preparing said polymer. Also provided is a composition comprising the polymer and a nucleic acid and/or polypeptide, and a method of delivering a nucleic acid and/or polypeptide to a cell.

Cationic polymer and use for biomolecule delivery

Provided is a polymer comprising a structure of Formula 1 or Formula 3 as provided herein, as well as a method of making the same; a composition comprising the polymer and a nucleic acid and/or polypeptide; and a method of delivering a nucleic acid and/or polypeptide to a cell.

Cationic polymer with alkyl side chains and use for biomolecule delivery

Provided are active agent delivery devices configured to deliver an active agent formulation into or through a mucosal layer in a subject. The active agent delivery devices include a power reservoir configured to eject the active agent formulation at a pressure sufficient to deliver the active agent formulation into or through a mucosal layer in a subject. Methods of using the subject active agent delivery devices are also provided.

Active agent delivery devices and methods of using the same

The invention provides a modified guide RNA comprising an extension sequence, as well as related compositions and methods.

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Berkeley, CA, United States of America

Kunwoo Lee