Fujifilm Corporation

Udc Ireland Limited

Kuniyuki Kaminaga

Ryuta Takegami

Wataru Sotoyama

Keisuke Kodama

Masaru Kinoshita

Kazuhiro Hasegawa

Yusuke Mochizuki

Koji Takaku

Toshihiro Ise

Tetsu Kitamura

Satoshi Sano

Yosuke Yamamoto

Yuki Hirai

Sotaro Inomata

Kazuomi Inoue

Tetsufumi Takamoto

Tenka Ouyo

Daisuke Inoue

Yasunori Yonekuta

Tadanori Yamada

Akihito Fukunaga

Heijiro Hirayama

Yuusuke Iizuka

Kenichi Yamamoto

Kazuhide Kanemura

Toshiki Takei

Naruhiko Aono

Yoshiyuki Kamide

According to the present invention, there are provided a chamber for transplantation, as a planar chamber for transplantation which has a structure in which membranes for immunoisolation face each other, and which is capable of stably enclosing a biological constituent, including a membrane for immunoisolation at a boundary between an inside and an outside of the chamber for transplantation, in which the membranes for immunoisolation which face each other have joint portions that are joined to each other, an interior space includes a point at a distance of 10 mm or longer from any position of the joint portion, and the membrane for immunoisolation has flexibility that allows a distance of 1 mm to 13 mm as the following distance: in a case where a portion of 10 mm from a side surface of one short side of a 10 mm×30 mm rectangular test piece of the membrane for immunoisolation is vertically sandwiched between flat plates, and the flat plates are placed horizontally, a distance between a horizontal plane including a center plane in a thickness direction of the sandwiched portion of the membrane for immunoisolation, and a part, which is farthest from the horizontal plane, of a residual 20 mm-portion projecting from the flat plate; and a device for transplantation including the chamber for transplantation enclosing a biological constituent therein.

Chamber for transplantation and device for transplantation

According to the present invention, there are provided a chamber for transplantation, including a membrane for immunoisolation including a porous membrane at at least part of a boundary between an inside and an outside of the chamber for transplantation, in which the porous membrane contains a polymer and has a layered compact portion where a pore diameter is the smallest within the membrane, a pore diameter continuously increases in a thickness direction from the compact portion toward both one surface A and the other surface B of the porous membrane, a porosity in a vicinity of the surface A is 65% or more, an average pore diameter of the surface A is larger than an average pore diameter of the surface B, and the surface B is disposed on the inside of the chamber for transplantation; and a device for transplantation including the chamber for transplantation enclosing a biological constituent therein. In the chamber for transplantation of the present invention, angiogenesis in a recipient is induced and a deterioration in substance permeability is unlikely to occur.

According to the present invention, there are provided a chamber for transplantation which has a high durability, and in which an enclosed biological constituent can be maintained for a long period of time because an interior space thereof is efficiently secured; and a method for manufacturing the chamber for transplantation. The chamber for transplantation includes one or more membranes for immunoisolation at a boundary between an inside and an outside of the chamber for transplantation, in which all of the membranes for immunoisolation include a porous membrane containing a polymer, and a joint portion at which the porous membranes are directly fusion welded to each other is provided. The method for manufacturing a chamber for transplantation includes preparing one or more porous membranes containing a polymer selected from polysulfone and polyethersulfone, bringing one part of the porous membrane into direct contact with another part of the porous membrane, and performing a heat fusion welding of the two parts that are in direct contact with each other at a temperature which is a glass transition temperature of the polymer or higher and lower than a melting point of the polymer.

Chamber for transplantation, method for manufacturing chamber for transplantation, device for transplantation, and method for fusion welding porous membranes

According to the present invention, there are provided a chamber for transplantation, as a planar chamber for transplantation which has a structure in which membranes for immunoisolation face each other, and which is capable of stably enclosing a biological constituent, including a membrane for immunoisolation at a boundary between an inside and an outside of the chamber for transplantation, in which the membranes for immunoisolation which face each other have joint portions that are joined to each other, an interior space includes a point at a distance of 10 mm or longer from any position of the joint portion, and the membrane for immunoisolation has flexibility that allows a distance of 1 mm to 13 mm as the following distance: in a case where a portion of 10 mm from a side surface of one short side of a 10 mm&#xd7;30 mm rectangular test piece of the membrane for immunoisolation is vertically sandwiched between flat plates, and the flat plates are placed horizontally, a distance between a horizontal plane including a center plane in a thickness direction of the sandwiched portion of the membrane for immunoisolation, and a part, which is farthest from the horizontal plane, of a residual 20 mm-portion projecting from the flat plate; and a device for transplantation including the chamber for transplantation enclosing a biological constituent therein.

An object of the present invention is to provide a separation substrate having a high megakaryocyte blocking rate and a high platelet permeation rate, and a cell separation filter and a method for producing a platelet which use the same. The separation substrate of the present invention is a separation substrate including non-woven fabric for separating a platelet from a cell suspension containing a megakaryocyte and the platelet, in which an average pore diameter of the separation substrate is 2.0 &#x3bc;m to 15.0 &#x3bc;m, and a thickness of the separation substrate is 10 &#x3bc;m to 500 &#x3bc;m.

Separation substrate, cell separation filter, and method for producing platelet

An organic electroluminescent element including a substrate, a pair of electrodes including an anode and a cathode, disposed on the substrate, and at least one layer of organic layers including a light emitting layer, disposed between the electrodes, in which at least one of the organic layers contains a compound represented by the following general formula: (Rto Reach independently represent a hydrogen atom or a substituent, and at least one of Rto Rand Rto Rrepresents -L-NRR(Rand Reach independently represent any of an alkyl group, an aryl group, a heteroaryl group. Rand Rmay be combined to each other to form a ring. L represents a single bond or a divalent linking group). Xto Xeach independently represent a carbon atom or a nitrogen atom, and when Xto Xrepresent nitrogen atoms, Rto Rfor bonding do not present.)

Organic electroluminescent element, compound and material for organic electroluminescent element capable of being used therefor, light emitting device, display device, and illumination device, each using the element

Disclosed is an organic electroluminescent element which is excellent with respect to luminous efficiency and driving voltage and rarely undergoes initial luminance drop. Specifically disclosed is an organic electroluminescent element which comprises, on a substrate, a pair of electrodes composed of an anode and a cathode and a light-emitting layer arranged between the electrodes, and additionally comprises at least one organic layer arranged between the light-emitting layer and the cathode, where in the light-emitting layer contains, for example, a compound (A-1), and the at least one layer arranged between the light-emitting layer and the cathode contains, for example, a compound (e-4). 

Organic electroluminescent element

There are provided an ion-exchange polymer including a structure represented by the following General Formula (1) and a production method therefor, an electrolyte membrane and a production method therefor, and a composition for producing an ion-exchange polymer.  In a case where the sum of a1, b1, and c1 is 1.000, a1 is 0.000 to 0.750, b1 is 0.240 to 0.990, and c1 is 0.001 to 0.100. L represents an alkylene group, Land Leach represent a divalent linking group, Ris a hydrogen atom or an alkyl group, Rand Reach represent an alkyl group or an allyl group, Xand Xeach represent an inorganic or organic anion, and Y represents a halogen atom. Zrepresents &#x2014;O&#x2014; or &#x2014;NRa&#x2014;, and Ra represents a hydrogen atom or an alkyl group.

Ion-exchange polymer and production method therefor, electrolyte membrane and production method therefor, and composition for producing ion-exchange polymer

A functional polymer membrane including a porous support and a crosslinked polymer electrolyte, in which the film thickness of the functional polymer membrane is smaller than 100 &#x3bc;m, the crosslinked polymer electrolyte is a crosslinked polymer formed by subjecting a composition including a monomer having a (meth)acrylamide skeleton to a polymerization curing reaction, and the proportion of elemental oxygen in the elemental composition excluding elemental hydrogen and helium at the surface of the porous support is from 14.0 atom % to 25.0 atom %; and a method for producing the same are provided.

Functional polymer membrane and method for producing same

There is provided a curable composition including a water-soluble acrylamide monomer represented by the following General Formula (1-1) or (1-2), a polymer functional cured product, a water-soluble acrylamide compound, and a method for manufacturing the same. In General Formulas (1-1) and (1-2), m represents an integer of 2 or greater, and L represents an m-valent group or a single bond. Here, in a case where L is a single bond, m is 2. Land Leach represent a single bond or a divalent linking group. Rto Reach represent a hydrogen atom or a substituent, and may be bonded to each other to form a ring, and may be bonded to L, L, or Lto form a ring. Either one of Rand Rrepresents a group represented by General Formula (a), and the other represents a group represented by General Formula (b).

Curable composition, polymer functional cured product, water-soluble acrylamide compound, and method for manufacturing same

Provided are a curable composition including an amide compound that is represented by Formula (1) below and of which a density of sulfonic acid is 3.9 milliequivalent/g or greater. 

Curable composition

An ion exchange membrane of the present invention contains a resin having an amino group and a constitutional unit represented by Formula 1, in which the number of amino groups per dry mass is 0.15 to 2.4 mmol/g. In Formula 1, Lrepresents an alkylene group or an alkenylene group, R, R, R, and Reach independently represent an alkyl group or an aryl group, Rand Rand/or Rand Rmay form a ring by being bonded to each other, n1 and n2 each independently represent an integer of 1 to 10, and Xand Xeach independently represent an organic or inorganic anion. 

Ion exchange membrane, method for manufacturing same, module, and device

An ion exchange membrane obtained by using an ionic monomer having at least two or more polymerizable functional groups, in which a hydrophobicity index H obtained by an expression below from a monomer for forming an ion exchange resin and a material fixed to the resin in the ion exchange membrane is 1.6 or greater, and a manufacturing method therefor. Hydrophobicity index H=&#x3a3;{(log P of each component)&#xd7;(molar ratio of each material in resin)}.

Ion exchange membrane and method for manufacturing the same

An organic electroluminescent element that includes a light-emitting layer composed of a light-emitting composition containing at least one type of host material and at least one type of light-emitting material is provided. The host material is a fluorescent anthracene derivative, which fluoresces blue light under DC current with a current density of 25 mA/cm. If &#x3bb; (nm) is taken to be the shortest wavelength of all the wavelengths at which the intensity of PL emission of a film composed only of the aforementioned host material is one-half the maximum emission intensity, then the intensity of PL emission at the aforementioned wavelength &#x3bb; of a film composed of the aforementioned light-emitting composition is no more than 1/10 the maximum emission intensity of PL emission of the film composed of the aforementioned light-emitting composition, and the PL emission of the film composed of the aforementioned light-emitting composition satisfies CIE y&#x2266;0.08.

Organic electroluminescent devices

This application relates in part to an organic electroluminescent element including a substrate, a pair of electrodes including an anode and a cathode, disposed on the substrate, and an organic layer(s) including a light emitting layer, in which the organic layer(s) contains a compound represented by the following formula (1), in which Rto Rare each hydrogen or a substituent, at least one of Rto Rand at least one of Rto Rare each a substituent represented by the formula (2); Rto R, Zto Z, Ar, Ar, and Lare as defined herein. 

Organic electroluminescent element, material for organic electroluminescent element and light emitting device, display device, and illumination device, each employing organic electroluminescent element

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Kanagawa, Japan

Kuniyuki Kaminaga