J. W. Broadbent Nominees Pty. Ltd.

Other

Suntory Holdings Limited

Pola Chemical Industries, Inc.

Tokai Denka Kogyo Kabushiki Kaisha

Daicho Kikaku Incorporated Company

Kuniro Tsuji

Hitoshi Ishida

Takuo Kosuge

Yoshiki Kosuge

Haruo Nukaya

Yoshiyuki Ishikura

Masanori Okada

Yasuhiro Kanaya

Yasunori Inaoka

Takao Daicho

Kenkichi Okada

Oto Miura

Akio Ochiai

Masaki Kosuge

Junichi Shibata

A muscle-strengthening, anti-inflammatory, antiasthmatic, antidiarrheal or an antidepressant method, or a method for the treatment of diminution of vision, hepatitis, inflammatory intestinal syndrome, functional enteropathy, functional hepatopathy, functional nephropathy, dementia, climacteric symptoms, senile dementia and/or Alzheimer disease, said method comprising: administering to skin a composition comprising (a) at least one member selected from the group consisting of isoflavones and isoflavone glycosides, (b) curcumin, and (c) cholic acid or at least one member selected from the group consisting of scymnol and scymnol esters.

Muscle-strengthening drugs and anti-inflammatory drugs

The present invention relates to novel flavone C-glycoside derivatives or salts thereof, especially those showing an anti-allergic effect, and compositions containing them. Recently, cases of allergic diseases, especially pollenosis and atopic dermatitis have increased to such a degree that they have become a social problem. Flavones and their glycosides have been reported to have the effect of inhibiting histamine release from mast cells or an immunosuppressive effect and expected for application as allergy therapies. However, most flavones exhibit their effects only at high doses, so that effective compounds at lower doses are highly desired. The present invention provides novel components capable of treating allergic diseases at low doses and compositions containing them.

Flavone C-glycoside derivatives and compositions containing the derivatives

Blood flow amount-improving agent comprising steroid derivative and

A compound of general formula, in substantially pure form, wherein A is a cation. A method for preparation is also disclosed, together with compositions and methods of use thereof. The active principle, isolated from shark tissue, is used for treating liver disfunction, or protecting liver function, in mammals.

Method of treating liver disfunction in mammals, using active principle

A compound of general formula, in substantially pure form, wherein A is a cation. A method for preparation is also disclosed, together with compositions and methods of use thereof.

Active principle isolated from shark tissue

The present invention relates to 24R-scymnol, including its preparation in substantially pure form and to its use in the treatment of liver dysfunction.

Method of treating liver dysfunction with 24-R scymnol

A crystallized, stable histidine-hydrogen peroxide adduct intermolecular-bonded at 1:1 ratio is provided.

Histidine-hydrogen peroxide adduct and process for preparing same

Derivatives of scymol sulfate

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Shizuoka, Japan

Kuniro Tsuji