Snow Brand Milk Products Co., Ltd.

Kunio Tomitsuka

Masamichi Nakakoshi

Susumu Ishiguro

Shin Nomoto

Shinichi Shimada

Masayuki Okue

Motohide Seya

Nobuo Ogane

Noboru Kawaguchi

Yuzo Yagi

Naomi Kito

Yasunari Saito

Particular hexahydropyrano [3,2-b] [1,4] benzothiazine derivatives represented by the following general formula (I) or pharmaceutically acceptable acid-addition salts thereof. ##STR1## The compounds can facilitate the metabolic turnover of inositol phospholipids at a hippocampus playing an important part in memory, and improve cerebral function leading the memory. The compounds can be utilized as agents for activating brain metabolism and improving cerebral function.

Hexahydropyrano [3,2-B] [1,4] benzothiazine derivative

Growing community of inventors

Kazo, Japan

Kunio Tomitsuka