Council of Scientific and Industrial Research

Kunal Sharan

Abhishek Kumar Singh

Rakesh Maurya

Girish Kumar Jain

Naibedya Chattopadhyay

Sabyasachi Sanyal

Arun Kumar Trivedi

Lakshmi Manickavasagam

Jiaur Rahaman Gayen

Nidhi Singh

Kamal Ram Arya

Manisha Yadav

Jay Sharan Mishra

Shailendra Kumar Dhar Dwivedi

Preety Dixit

Preeti Rawat

Jawed Akhtar Siddiqui

Gaurav Swarnkar

Geetanjali Mishra

Smrati Bhadauria

Parvez Mohammad Khan

Kainat Khan

Devendra Pratap Mishra

Sharad Sharma

Ram Arya Kamal

The present invention provides a flavonol compound and a bioactive extract/fraction fromuseful for the management or prevention or treatment of bone disorders. Said extract/fraction comprising marker compounds of general formula 2, K058: R&#x2550;R&#x2550;OH K012: R&#x2550;R&#x2550;OH, 2,3 double bond K068: R&#x2550;R&#x2550;H KIOOi R&#x2550;OH, R&#x2550;H mula 2 Wherein the marker compounds K012, K058, K068, K1OO ranges 6.7-12%, 1.7-4.5%, 0.6-1.2%, 1.7-4.5% respectively in alcoholic extract and a process of extraction thereof. According to another aspect of the invention provides a pharmaceutical composition comprising the said compound. The present invention further provides a method of treating bone disorders by administering the pharmaceutical composition by oral, intravenous, subcutaneous, intra-peritoneal or intramuscular route. 

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Kunal Sharan