Northwestern University

University of Illinois

Rehabilitation Institute of Chicago

Kun Hyuck Lee

John A Rogers

Arun Jayaraman

Jungil Choi

Shuai Xu

Tyler R Ray

Philipp Gutruf

Siddharth Krishnan

Jonathan T Reeder

Chun-Ju Su

Amit B Ayer

Sungbong Kim

Johnathan T Reeder

Yurina Sekine

Amay J Bandodkar

Aurelie Hourlier-Fargette

Ha Uk Chung

Jong Yoon Lee

Milan Raj

Alina Rwei

Leora Cherney

Edna Babbitt

Bonnie Martin-harris

Xiaoyue Ni

Angela Roberts

Megan O'BRIEN

The invention provides a versatile sensing platform for sensing and analysis of biofluids, particularly well-suited for sensing and analysis of sweat. Systems of the invention allows for sensitive and selective detection of a range of analytes in sweat including metabolites, electrolytes and biomarkers. Systems of the invention provide a noninvasive and accurate means for quantitative characterization of important sweat characteristics including sweat volume, sweat loss and sweat rate. Systems of the invention are compatible with materials and device geometries for important class of conformal tissue mounted electronic devices, including epidermal electronic devices.

Epidermal sensing systems for optical readout, visualization and analysis of biofluids

Provided are conformable devices to measure subdermal fluid flow and related methods. A soft, stretchable and flexible substrate supports a thermal actuator and various specially positioned temperature sensors. A microprocessor in electronic communication with sensors calculates subdermal fluid flow from the measured upstream and downstream temperatures, as well as various application-dependent parameters. Devices and methods provided herein are particularly useful for measuring cerebral spinal fluid in a ventricular shunt placed for treatment of hydrocephalus.

Wireless and noninvasive epidermal electronics

Growing community of inventors

Morton Grove, IL, United States of America

Kun Hyuck Lee