Shimadzu Corporation

Kumiko Jingu

Masanori Fujiwara

Tomoyuki Yamazaki

Yusuke Nagai

Masato Watanabe

Keisuke Ogawa

Masami Tomita

Yoshiaki Aso

Fujio Inoue

Yutaka Kono

The degassing device includes a degassing flow path, a vacuum chamber, a vacuum pump, an inlet flow path, an outlet flow path, a drain flow path, a downstream side switching unit, and a controller. The degassing flow path is made of a gas-permeable, liquid-impermeable tube, and is accommodated in the vacuum chamber. The inlet flow path is for introducing a mobile phase to the degassing flow path, and the outlet flow path is for causing a mobile phase which has passed through the degassing flow path to flow out. The drain flow path is provided separately from the outlet flow path and is configured to drain the mobile phase in the degassing flow path from the degassing flow path. The downstream side switching unit is configured to switch the downstream end of the degassing flow path so as to be connected to either the outlet flow path or the drain flow path. The controller controls the operation of the downstream side switching unit, and is configured to connect the downstream end of the degassing flow path to the drain flow path at a predetermined timing when feeding of the mobile phase by the liquid feeding pump is stopped to drain the mobile phase in the degassing flow path through the drain flow path.

Degassing device

A degassing deviceincludes: a built-in absorbance measurement sectionusing an LED light source and measuring the intensity of light transmitted through a mobile phase passing through a flow cell; and a solenoid valveswitchable between two states with and without the mobile phase passed through a degassing tube. The passage-switching operation by the solenoid valve is performed so as to obtain detection signals of the transmitted light in the absorbance measurement section when the mobile phase drawn from a mobile phase container by a liquid-feeding pumpis passed through the degassing tube for degassing as well as when the mobile phase is not passed through the degassing tube for degassing. A signal processorcalculates the difference in absorbance based on those detection signals, estimates the degree of degassing based on that difference, and displays the result on a display unit

A differential refractometer including a measurement section for measuring the diffractive index difference between a sample cell and a reference cell by radiating light on a measurement cell and detecting light which has sequentially passed through the sample cell and the reference cell includes a mobile phase supply section for delivering a mobile phase in a sample introduction channel that is connected to the sample cell. The mobile phase supply section includes a mobile phase container for containing the mobile phase. The inside of the mobile phase container is continuously stirred by a stirring mechanism, and the composition of the mobile phase inside the mobile phase container is made uniform.

Measurement method using differential refractometer, differential refractometer using the measurement method, and liquid chromatograph

Provided is an optical analyzer for performing a feedback control on the amount of light emitted from an LED as a light source, in which the configuration of an optical system is made simple and the degree of freedom in optical system arrangement is secured. An optical memberfor focusing most of light while discharging part of the light as unfocused light is provided on an optical path from a light casting unitto a sample cell. The optical membercan be achieved with a simple configuration, for example, two ball lenses spaced apart by a predetermined distance from each other. The light focused by the optical memberis cast as measurement light into the sample cell. Meanwhile, a second photodetectoris arranged at a position where the unfocused light reaches. The second photodetectorgenerates a detection signal in accordance with the amount of light that has entered the second photodetectoras monitored light, and a drive current to be supplied to an LED is controlled through a drive current controlling unitand a current sourcesuch that the amount of light is maintained at a fixed level.

Optical analyzer

A plunger seal has a cylindrical protruding portion on its front face. A base end portion of the protruding portion has a recessed curved shape having a certain curvature. In a portion of a pump head, where the plunger seal is mounted, a seal insertion portion into which the protruding portion of the plunger seal is to be fitted is formed as a cylindrical recessed portion. An opening edge portion of the seal insertion portion has a protruding curved shape having the same curvature as the base end portion of the protruding portion of the plunger seal.

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Kyoto, Japan

Kumiko Jingu