Eisai Company, Limited

Kumiko Hara

Shinya Abe

Isao Yamatsu

Yuichi Inai

Toshiji Igarashi

Hideaki Watanabe

Yoshio Tanabe

Hiroyuki Shiojiri

This invention relates to polyprenylcarboxylic acid amides represented by the following general formula (I): ##STR1## wherein n is an integer of from 1 to 4, a and b stand for hydrogen atoms or a direct valence bond between the carbon atoms to which a and b are attached, c and d stand for hydrogen atoms or a direct valence bond between the carbon atoms to which c and d are attached, and R.sub.1 and R.sub.2 stand for a hydrogen atom, a lower alkyl group, a phenyl group which may be substituted or an aralkyl group which may be substituted, or R.sub.1 and R.sub.2 form, together with the adjacent nitrogen atom, a 5- or 6-membered heterocyclic ring which may contain other hetero atoms or may be substituted, and also to a process for the preparation of said polyprenylcarboxylic acid amide and to a pharmaceutical composition for treating liver dysfunction comprising said polyprenylcarboxylic acid amide.

Polyprenylcarboxylic acid morpholides and pharmaceutical compositions

Polyprenyl carboxylic acid amides of the formula ##STR1## process for their preparation and use thereof for treating liver dysfunction are disclosed.

Polyprenylcarboxylic acid amides useful for treating liver dysfunction

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Tokyo, Japan

Kumiko Hara