Dr. Reddy's Laboratories, Incorporated

Kumar Sarvesh

Debjit Basu

Vilas Hareshwar Dahanukar

Rakeshwar Bandichhor

Prapulla Kumar Palvai

Uday Kumar Neelam

Sudhir Sai

Amit Kumar Mandal

Raja Gopal Penumandla

The present application relate to a process for preparation of 4-Methylene tetrahydrofuran compound of formula II, which is useful as an intermediate for the preparation of halichondrin B analogues such as Eribulin.

Process for preparation of eribulin and intermediates thereof

The present application relate to process for preparation of tetrahydrofuran compound of formula II, 4-Methylene tetrahydrofuran compound of formula V and tetrahydropyran compound of formula IX which are useful as intermediates for the preparation of halichondrin B analogues such as Eribulin or its pharmaceutically acceptable salts.

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Secunderabad, India

Kumar Sarvesh