Navi Bio-therapeutics, Inc.

Kuang-Yu Chen

Wei-Ting Hsu

Bor-Yu Tsai

Shin-Tsung Huang

The present disclosure relates to a method for obtaining an antibody or antigen-binding fragment thereof that specifically binds to and against a tumor sample, comprising: administering autologous dendritic cells to a subject; taking immune cells and a tumor sample from the subject; constructing an antibody library of the immune cells; and screening the antibody library to obtain the antibody or a fragment thereof specifically binding to and against the tumor sample. The disclosure also relates to a method for engineering immune cells, an antibody or antigen-binding fragment thereof that specifically binds to and against a tumor sample and uses thereof.

Growing community of inventors

Kaohsiung, Taiwan

Kuang-Yu Chen