Glaceum, Inc.

Ku Suk Kang

Sang Ku Yoo

Ji Young Kim

Jeong Ho Im

Jin Young Kim

Jin Wook Chung

In Geun Jo

Jung Woo Lee

Jin Sung Kim

Jeong Ho Lim

The present invention relates to a method for synthesizing a 2-((6-(hydroxymethyl)chromen-5-yl)oxy)-1-phenylethanone derivative. When the method is used, it is possible to effectively synthesize a 2-((6-(hydroxymethyl)chromene-5-yl)oxy)-1-phenylethanone derivative.

Method for synthesizing 2-((6-(hydroxymethyl)chromene-5-yl)oxy)-1-phenylethanone derivative

The present invention may provide an asymmetric hydrogenation catalyst capable of resolving enantiomers with excellent enantioselectivity from a carbon-carbon double bond-containing compound. The catalyst according to one embodiment of the present invention includes: an iridium cation; and a ligand bonded to the iridium cation.

Catalyst for asymmetric hydrogenation of compound containing carbon double bond

The present invention relates to a method for synthesizing a 3-phenyl-2,8-dihydropyrano[2,3-f]chromene derivative, which may be usefully used for synthesizing a pyranochromenyl phenol derivative, and when the derivative is used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative may be effectively prepared.

Method for synthesizing 3-phenyl-2,8-dihydropyrano [2,3-f] chromene derivative

The present invention relates to pyranochromenylphenol derivatives having different efficacies depending on the direction of optical activity and a pharmaceutical composition including the same, and in the pyranochromenylphenol derivatives, an R-enantiomer has excellent anti-diabetic efficacy by suppressing a rise in blood sugar and an S-enantiomer has excellent anti-obesity efficacy by suppressing an increase in body weight.

Optically active pyranochromenyl phenol derivative and pharmaceutical composition comprising same

The present invention relates to a method for synthesizing a 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and an optical isomer thereof, and an intermediate Compound which may be used for the synthesis method, and when the method and the intermediate Compound are used, the 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and the optical isomer thereof may be effectively synthesized.

3-phenyl-2,3,4,8,9,10-hexahydropyrano[2,3-f]chromene derivative and method for synthesizing optical isomer thereof

Method for synthesizing 3-phenyl-2,3,4,8,9,10-hexahydropyrano[2.3-f]chromene derivative and optical isomer of thereof

Provided are a pyranochromenyl phenol derivative, a pharmaceutically acceptable salt thereof, or a solvate thereof. Also provided is a pharmaceutical composition for preventing or treating metabolic syndrome or inflammatory disease comprising same. The present invention is efficacious in preventing or treating metabolic syndrome or inflammatory disease and is chemically stable.

Growing community of inventors

Yongin-si, South Korea

Ku Suk Kang