Unversität Zürich

Polyphor Ag

Krystyna Patora-Komisarska

Daniel Obrecht

John Anthony Robinson

Frank Otto Gombert

&#x3b2;-Hairpin peptidomimetics of the general formula Cyclo(-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-Xaa-), enantiomers and pharmaceutically acceptable salts thereof, with Xaa-Xaabeing amino acid residues of certain types which are defined in the description and the claims, have anti-infective activity, e.g. to selectively inhibit the growth of or to kill microorganisms such asand/or. They can be used as medicaments to treat or prevent infections or as disinfectants for foodstuffs, cosmetics, medicaments or other nutrient-containing materials. These peptidomimetics can be manufactured by a process which is based on a mixed solid- and solution phase synthetic strategy.

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Zurich, Switzerland

Krystyna Patora-Komisarska