Egis Gyogyszergyar Zrt.

Egis Gyogyszergyar Nyrt

Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag

Egis Gyogyszergyar

Krisztina Móricz

Gyula Simig

Gábor Gigler

Tibor Mezei

Gabor Gigler

Istvan Gacsalyi

Jozsef Barkoczy

József Barkóczy

Balázs Volk

György Lévay

Katalin Pallagi

István Gacsályi

László Gábor Hársing

András Egyed

Csilla Leveleki

Nóra Sziray

Rita Kapillerné Dezsöfi

Gabor Nemeth

Balazs Volk

Gábor Szénási

Istvan Ling

Andras Dancso

Zoltán Varga

Hajnalka Kompagne

Szabolcs Kertesz

Ferenc Antoni

Janos Petho

Lax Gyorgyi Kovanyine

Gábor Szenasi

Endréné Flórian

Agnes Kenez

Balazs Mihalik

György Levay

Dániel Ulej

Anita Gulyás

András Ferenc Wacha

Adrienn Pálvölgyi

Ferenc Bertha

Agnes Angyalne Pataki

Edit Pap

Attila Bóta

Marta Agoston

Adrienn Palvolgyi

Gabor Laszlo Kapus

Gyoergy Levay

Gabor Szenas

Lászlo Gabor Harsing

László Gábor Harsing

Márta Agoston

István Gacsalyi

József Barkoczy

The present invention relates to a topical pharmaceutical composition comprising pregabalin and a reduced micellar phospholipid as an active ingredient, which results in a prolonged analgesic effect of pregabalin. The product can reduce neuropathic pain by at least 5 hours.

Topical pharmaceutical composition containing phospholipids

Compounds of formula (I) having a selective dual action on the central GABAergic system, and a process for their preparation and to pharmaceutical compositions containing them.

Dihydro-oxazinobenzodiazepine compounds, a process for their preparation and pharmaceutical compositions containing them

The invention relates the use of 4-chloro-5-{2-[4-(6-fluoro-1,2-benz[d]isoxazole-3-yl)piperidin-1-yl]ethyl-amino}-2-methyl-3-(2H)pyridazinone of the Formula (I) or pharmaceutically acceptable salts thereof for the preparation of medicaments suitable for the improvement of cognitive function or obtaining neuroprotective effect. The medicaments containing 4-chloro-5-{2-[4-(6-fluoro-1,2-benz[d]isoxazol-3-yl)piperidin-1-yl]ethyl-amino}-2-methyl-3-(2H)pyridazinone of the Formula (I) or therapeutically acceptable salt thereof can be used for the treatment or prevention of neuronal death, mental decline, sclerosis multiplex, Creuzfeld-Jacobs disease, Huntington-syndrome, amyotrophic lateral sclerosis, Parkinson-disease, memory disturbance, loss of memory, amnesia, stroke or for the improvement of memory function or learning ability.

Medicament for the enhancement of cognitive function and neuroprotection

The present invention is concerned with new indol-2-one derivatives of Formula (I), which have favorable activity profile for the prophylaxis and treatment of disorders in the central nervous or in the cadiovascular system. 

Piperazine derivatives of alkyl oxindoles

The present invention is concerned with new 3,3-disubstituted indol-2-one derivatives of the general Formula (I), wherein Rstands for hydrogen, halogen, alkyl having 1-7 carbon atom(s) or sulfonamido; Rrepresents hydrogen or halogen; Rdenotes hydrogen, alkyl having 1-7 carbon atom(s) optionally carrying an aryl substituent or aryl optionally carrying one or two halogen substituent(s); Rstands for alkyl having 1-7 carbon atom(s); Rrepresents a group of the general Formula (II a) or (II b), wherein Q and W each represents nitrogen or CH; R, Rand Reach stands for hydrogen, halogen, trifluoromethyl, alkyl or alkoxy having 1-7 carbon atom(s), or Rand Rtogether represent ethylenedioxy; m is 0, 1, or 2; a is a single, double or triple bond; n is 0, 1 or 2; and pharmaceutically acceptable acid addition salts thereof which are useful in the treatment or prophylaxis of diseases of the central nervous system, the gastrointestinal system and the cardiovascular system. 

Piperazine derivatives of dialkyl oxindoles

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Budapest, Hungary

Krisztina Móricz