Biolipox Ab

Kristofer Olofsson

Benjamin Pelcman

Ivars Kalvins

Edgars Suna

Vita Ozola

Martins Katkevics

Dace Katkevica

Peteris Trapencieris

Wesley Schaal

Vita Latvian Institute Of Organic Synthesis Ozola

Peteris Latvian Inst Of Organic Synthesis Trapencieris

Dace Latvian Inst Of Organic Synthesis Katkevica

Edgars Latvian Inst Of Organic Synthesis Suna

Martins Latvian Inst Of Organic Synthesis Katkevics

Ivars Latvian Inst Of Organic Synthesis Kalvins

 There is provided compounds of formula (I), wherein X, Q, T, Y, R, R, R, Rand Rhave meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a member of the MAPEG family is desired and/or required, and particularly in the treatment of inflammation.

Indoles useful in the treatment of inflammation

There is provided a compound of formula: (I), wherein X, R, R, R, R, Rand Rhave meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of microsomal prostaglandin E synthase-1 is desired and/or required, and particularly in the treatment of inflammation. 

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Solna, Sweden

Kristofer Olofsson