Berkeley Lights, Inc.

Bruker Cellular Analysis, Inc.

Kristin G Beaumont

Randall D Lowe, Jr

Mark P White

J Tanner Nevill

Daniele Malleo

Andrew W McFarland

Aathavan Karunakaran

Gregory G Lavieu

Volker L S Kurz

Xiaohua Wang

Alexander J Mastroianni

Kevin T Chapman

Jason M McEwen

Gang F Wang

Xiao Guan

Natalie C Marks

Keith J Breinlinger

Troy A Lionberger

Peter J Beemiller

Yelena Bronevetsky

Nan-Linda Ding

Jr Lowe Randall D

Keith Joseph Breinlinger

Andrew W Mcfarland

Volker L Kurz

Jr Randall D Lowe

In biosciences and related fields, it can be useful to modify surfaces of apparatuses, devices, and materials that contact biomaterials such as biomolecules and biological micro-objects. Described herein are surface modifying and surface functionalizing reagents, preparation thereof, and methods for modifying surfaces to provide improved or altered performance with biomaterials.

Covalently modified surfaces, kits, and methods of preparation and use

In situ-generated microfluidic isolation structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. The ability to introduce in real time, a variety of isolating structures including pens and barriers offers improved methods of micro-object manipulation in microfluidic devices. The in situ-generated isolation structures may be permanently or temporarily installed.

In situ-generated microfluidic isolation structures, kits and methods of use thereof

Systems, methods and kits are described for culturing one or more biological cells in a microfluidic device, including provision of nutrients and gaseous components configured to enhance cell growth, viability, portability, or any combination thereof. In some embodiments, culturing a single cell may produce a clonal population in the microfluidic device.

Microfluidic cell culture

In situ-generated microfluidic capture structures incorporating a solidified polymer network, methods of preparation and use, compositions and kits therefor are described. Microfluidic capture structures may be advantageously used for assays performed within the microfluidic environment, providing flexibility in assaying micro-objects such as biological cells. Assay reagents and analytes may be incorporated within the microfluidic capture structures.

In situ-generated microfluidic assay structures, related kits, and methods of use thereof

Growing community of inventors

New York, NY, United States of America

Kristin G Beaumont