Albany Molecular Research, Inc.

Bristol-myers Squibb Compnay

Kristen N Ryan

Richard Eric Olson

Shuang Liu

Peter Guzzo

Bruce Francis Molino

John E Macor

David Douglas Manning

Matthew L Isherwood

Kassoum Nacro

Wenge Cui

Aruna Sambandam

Min Hu

Congxiang Zha

Russell DeOrazio

The compounds of the present invention are represented by the following aryl- and heteroaryl-substituted tetrahydrobenzazepine and dihydrobenzazapine derivatives having formulae I(A-E) and formula (II): where the carbon atom designated * is in the R or S configuration, and the substituents X and R-Rare as defined herein.

Aryl- and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

The compounds of the present invention are represented by the following 2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives having formula (I): where the carbon atom designated * is in the R or S configuration when n is 1 and the substituents X and R-Rare as defined herein.

2,5-methano- and 2,5-ethano-tetrahydrobenzazepine derivatives and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

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Clifton Park, NY, United States of America

Kristen N Ryan