Albany Molecular Research, Inc.

Bristol-Myers Squibb Compnay

Kristen N Fleming

Richard Eric Olson

Shuang Liu

Peter Guzzo

Bruce Francis Molino

David Douglas Manning

Matthew L Isherwood

Kassoum Nacro

Wenge Cui

Min Hu

Aruna Sambandam

Congxiang Zha

The compounds of the present invention are represented by the following aryl- and heteroaryl-substituted tetrahydrobenzazepine and dihydrobenzazapine derivatives having formulae I(A-E) and formula (II): where the carbon atom designated * is in the R or S configuration, and the substituents X and R-Rare as defined herein.

Aryl- and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin

The compounds of the present invention are represented by the following aryl- and heteroaryl-substituted tetrahydrobenzazepine and dihydrobenzazapine derivatives having formulae I(A-E) and formula (II):  where the carbon atom designated * is in the R or S configuration, and the substituents X and R-Rare as defined herein.

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Clifton Park, NY, United States of America

Kristen N Fleming