Cook Medical Technologies LLC

Cook Biotech, Inc.

Krista Gearhart

Umesh H Patel

Steven Charlebois

Keith Milner

Bhavin Shah

Priscilla Reyes

Rhonda Peck

Angela Rose Barnett

Eric J Rodenberg

Aparna Reddy Sarasam

Jason Lichti

The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.

Drug eluting graft constructs and methods

A coated medical device, such as a stent, that elutes a taxane agent in a controlled manner is provided. In one embodiment, the taxane agent is paclitaxel and at least a portion of the paclitaxel is present in a dihydrate solid form. The medical device may be coated with a layer including a taxane agent and a layer of bioabsorbable elastomer over the layer including the taxane agent. Methods of manufacturing and using the coated medical device are also provided.

Implantable medical device coatings with biodegradable elastomer and releasable taxane agent

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Lafayette, IN, United States of America

Krista Gearhart