USA As Represented by Secretary of the Navy

Alion Science and Technology Corporation

Krishnaswamy S Rajan

Vinod S Agarwala

Alfeo A Conte, Jr

Stephen S Mainer

Prabir K Sen

Methods and devices are provided for the detection of bacterial agents such agents asandwith high sensitivity and selectivity. More specifically, methods and devices are based on a phosphorescence-emission detection system using chelate-stabilized lanthanides (e.g, Eu(III), Tb(III), and Sm(III)) to detect various spore-specific small organic molecules (e.g., dipicolinic acid, diaminopimelic acid, n-acetlymuramic acid, and the like). By careful selection of the chelating agent or ligand coordinated to the lanthanide, both high specificity and selectivity can be obtained. Examples of suitable and preferred sensor systems include N-(2-hydroxyethyl)ethylenediaminetriacetic acid (HEDTA) and N-(2-hydroxyethyl)iminodiacetic acid (HEIDA) combined with europium (III) and/or terbium (III). The chelate-stabilized lanthanides react with the spore-specific 'target' molecules to form a characteristically phosphorescent product which can then be detected.

Detection of biological warfare agents

This invention relates to a method and composition for improving the corron resistance and anti-wear properties of synthetic lubricating oil greases comprising the addition to said greases of effective amounts of a chelated Schiff base derived from the condensation of approximately stoichiometic amounts of at least one aldehyde and a polyamine.

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Elmhurst, IL, United States of America

Krishnaswamy S Rajan