Alexza Pharmaceuticals, Inc.

Itrace Biomedical Inc.

Eastman-kodak Company

Juul Labs, Inc.

Alexza Pharmauceticals, Inc.

Krishnamohan Sharma

Joshua D Rabinowitz

Mingzu Lei

Dennis Solas

Ron L Hale

Joseph F Bringley

Pravin L Soni

Martin J Wensley

Curtis Peter Tom

Daniel J Myers

Reynaldo J Quintana

Soonho Song

Namhey Lee

Ramesh Damani

Radhakrishnan Ramdas

Anusha Saripalli

Peter Lloyd

Kenneth James Lushington

Gary Norman Barber

Kristopher P Diokno

Samira Bagheri

Patrik Munzar

Kartik Karri

Matthew D Stracker

Bhaskara Rao Bandaru

Bhaskara Rao Bandura

Bryson Bennett

Dennis W Solas

Amy T Lu

Compositions include an aqueous organic-based gellant system and nicotine or a salt thereof. The compositions are readily prepared and stored in cartridges or used directly in a device for delivering nicotine to a user.

Organic-based nicotine gel compositions

A vaporization device includes a vaporizer cartridge having a reservoir that holds a vaporizable material, a heating element, and a gel wicking element that can draw the vaporizable material to the heating element to be vaporized. The vaporizer cartridge is configured for coupling to a vaporizer device body and containing a vaporizable material. Various embodiments of the vaporizer cartridge are described that include one or more features for the wicking element. Various embodiments of the wicking element, as well as related systems, methods, and articles of manufacture are also described.

Gels wicks for vaporizer devices

A heating unit comprising an electrically conductive substrate. A solid fuel layer comprising a metal reducing agent, a metal containing oxidizing agent and a binder is coated on a surface of the substrate, the solid fuel layer having a solid fuel surface spaced from the substrate. A first electrode coupled to the substrate. A second electrode coupled to the solid fuel surface. A power supply is configured to be selectively coupled to the first and second electrodes to provide a voltage between the metallic substrate and the solid fuel surface. The voltage acts to propagate an exothermic metal oxidation-reduction reaction without the use of an igniter.

Heat units using a solid fuel capable of undergoing an exothermic metal oxidation-reduction reaction propagated without an igniter

Systems and methods disclosed herein provide efficacious pain management therapies based on delivery of physical medicine(s) via computer-implemented systems. Patient information comprising patient pain symptoms, patient physiological measurements, patient demographics, and other information is received at a pain therapy device. The patient information is compared with pain analytics data compiled on a plurality of individuals to determine a personalized pain management therapy. The personalized pain management therapy is applied via a combination of thermoceuticals, electroceuticals, ultrasound, and several other forms of physical medicine. Sensors coupled to the pain therapy device measure changes in physiological data resulting from the pain management therapy. The personalized pain management therapy can be adjusted based on the changes in the physiological data and/or patient feedback. The patient information, information about the applied therapy, and therapy outcome information is added to the analytics database.

Personalized pain management treatments

The present disclosure relates to an electronic therapy device including automatic controlled application of energies along with feedback control using sensors for improved synergistic effects and further the device is configured to be used for longer periods of time for improved and optimal therapeutic results without causing any adverse effects, the device can be used for pain management, healing, fitness, cosmetic and topical delivery related applications and a method for performing electronic therapy using the said portable electronic device.

Portable electronic therapy device and the method thereof

The present invention relates to an active transdermal analyte detection system performing extraction and detection of body analytes comprising of a patch accepting at least one electrical input; a plurality of transducers configured for converting input electrical energy to different forms of energies for activating extraction procedure; a controller configured for providing the control signals, intensity, sequence, nature, and timing information for the different energies supplied to the said patch vide said transducers; and at least one layer/compartment configured for either collection of extracted fluids and/or delivering at least one reagent formulation that detects the body analyte on activation and a method for performing transdermal extraction and detection of body fluids using said electronic patch.

Transdermal analyte extraction and detection system and the method thereof

Heating units, drug supply units and drug delivery articles capable of rapid heating are disclosed. Heating units comprising a substrate and a solid fuel capable of undergoing an exothermic metal oxidation reaction disposed within the substrate are disclosed. These heating units can be actuated by electrical resistance, by optical ignition or by percussion. Drug supply units and drug delivery articles wherein a solid fuel is configured to heat a substrate to a temperature sufficient to rapidly thermally vaporize a drug disposed thereon are also disclosed.

Self-contained heating unit and drug-supply unit employing same

Aerosol drug delivery devices incorporating percussively activated heat packages are disclosed. The heat packages include a percussive igniter and a fuel capable of undergoing an exothermic oxidation-reduction reaction when ignited by the percussive igniter. The drug delivery devices disclosed can be activated by an actuation mechanism to vaporize a thin solid film comprising a drug disposed on the exterior of a hat package. Metal coordination complexes of volatile drugs, and in particular nicotine, from which the drug can be selectively vaporized when heated are also disclosed. The use of aerosol drug delivery devices comprising thin films of nicotine metal salt complexes for the treatment of nicotine craving and for effecting smoking cessation are also disclosed.

Aerosol drug delivery device incorporating percussively activated heat packages

A photographic element is described comprising a support bearing one or more hydrophilic colloid layers including at least one photographic silver halide emulsion layer, wherein a photographically useful compound is incorporated into at least one hydrophilic colloid layer in the form of an intercalation composition comprising a layered host material having molecules of the photographically useful compound inserted as guest molecules between the layers of the host material. The invention provide novels materials and a method of incorporating active chemistry compounds such as developers or development inhibitors directly into a photographic imaging element with improved stability and keeping response versus known methods for incorporating active chemistry compounds.

Silver halide imaging element containing intercalated photographically useful compounds

A recording element comprising a support having thereon an image-receiving layer, said recording element containing core-shell particles wherein said core comprises an inorganic or organic particle and said shell comprises an organosilane or a hydrolyzed organosilane derived from a compound having the formula:Si(OR)Zwherein

Inkjet recording element

Growing community of inventors

Milpitas, CA, United States of America

Krishnamohan Sharma