Nicoya Lifesciences Inc.

P&p Optica Inc.

Krishna Iyer

Ryan Denomme

Gordon H Hall

Arjun Sudarsan

Romuald Pawluczyk

Ewa Maria Osika

Timothy M F Stork

Anthony Robert Shaw

Alexander Baran-Harper

Jason Garr

David William Lizius

Patrick Sterlina

Olga Ewa Pawluczyk

Lee-Anne Stossell

Bradley Oldenburg

Simon Guthrie

Charles Curbbun

Champika Samarasekera

Shawn Fitzpatrick

Eikky Lim Eng Kuan

Trang Tina Thi Thuy Nguyen

Mandy Lubjenka

Ryan Cameron Denomme

Timothy MF Stork

The present invention is directed to microfluidics systems, instruments, and cartridges including self-aligning optical fiber systems and methods of use thereof. More specifically, the disclosure describes a microfluidics instrument including an optical detection system, microfluidics cartridge, and a self-aligning optical fiber system capable of coupling the microfluidics instrument and the microfluidics cartridge. Further, the disclosure provides methods of optical detection operations using a microfluidics system.

Microfluidics system, instrument, and cartridge including self-aligning optical fiber system and method

A digital microfluidic (DMF) system, DMF cartridge, and method including integrated refractive index (RI) sensing is disclosed. The digital microfluidic DMF system and DMF cartridge may include, for example, a RI sensor (or sensor surface) directly in the droplet operations gap of a DMF cartridge. The digital microfluidic DMF system may include, for example, the DMF cartridge, one or more illumination sources, one or more optical measurement devices, and a controller. Additionally, a method of using the DMF system and DMF cartridge that includes integrated RI sensing is provided.

Digital microfluidic systems, cartridges, and methods including integrated refractive index sensing

A pipette dispenser vision system and method are disclosed. For example, a pipette dispenser vision system is provided for tracking pipettes with respect to dispensing liquid into target fluid wells, vessels, and/or reservoirs. The presently disclosed pipette dispenser vision system may include, for example, a computing device, a red/green/blue (RGB) imaging device, an infrared (IR) imaging device, an IR illumination source, and an IR sensor; all arranged with respect to, for example, a single-channel and/or a multi-channel pipette for dispensing liquid into a dispensing platform. Further, a method of using the presently disclosed pipette dispenser vision system is provided. For example, the method processes image data from the RGB imaging device and/or the IR imaging device to monitor/verify certain operations of the pipetting process and/or dispensing platform.

Pipette dispenser system and method

A plasmon resonance (PR) system, instrument, and/or device and configurations thereof for measuring molecular interactions is disclosed. In some embodiments, the PR system, instrument, and/or device is a localized surface plasmon resonance (LSPR) system, instrument, and/or device. In other embodiments, the PR system, instrument, and/or device is a surface plasmon resonance (SPR) system, instrument. The PR system, instrument, and/or device may include, for example, force feedback for reliable flow cell sealing, optical feedback for reliable flow cell sealing, local thermal control of an LSPR chip (e.g., a ring Peltier, a continuous Peltier), dual displacement pumps for constant flow delivery to a microfluidic device, a dual channel LSPR sensor, and any combinations thereof.

Plasmon resonance system, instrument, and device for measuring molecular interactions

Chemical analysis instrument

A device and system for optically analyzing food products is provided. The device comprises first and second imaging devices respectively sensitive to first and second wavelengths; the imaging devices include a line-scan camera to acquire images of food products at a line in a food-path-facing direction, and a line-scan spectrometer to acquire spectroscopic images at the line. The device includes an optical filter configured to: convey the first wavelengths from the line to the first imaging device; and convey the second wavelengths from the line to the second imaging device. The device includes a frame to align the optical filter and respective optical axes of the first and second imaging devices, relative to each other and the food-path-facing direction, such that the first imaging device and the second imaging device are optically aligned via the optical filter to image the line.

Device and system for optically analyzing food products

A lamp for illuminating food products along a line is provided. The lamp comprises: a housing having a longitudinal axis and an opening along the longitudinal axis; a light source located in the housing along the longitudinal axis; a reflector positioned in the housing along the longitudinal axis, the reflector to reflect light from the light source through the opening and focus the light along the line; a removeable frame attached to the housing around the opening, the removeable frame having an aperture aligned with the opening along the longitudinal axis; a glass window in the aperture; a transparent polymer film in the aperture at an outward facing side of the glass window, each of the glass window and the transparent polymer film extending into the removeable frame past a perimeter of the aperture; and a seal between the transparent polymer film and the perimeter of the aperture.

Lamp for illumination food products along a line

Growing community of inventors

Waterloo, Canada

Krishna Iyer