Kubota Corporation

Dainippon Sumitomo Pharma Co., Ltd.

Kozo Yoshida

Mitsugu Okuda

Ryu Nagata

Hiroyuki Nakahira

Hiroshi Manabe

Yohei Ikuma

Hidenori Kimura

Takashi Onishi

Nobuhisa Fukuda

Junya Ikeda

Masahiro Nagahama

Kiyoto Sawamura

Teruhisa Tokunaga

Kantaro Ushiroda

Satoshi Suetsugu

Yoshio Nakai

Makoto Kitoh

Katsunori Maruta

Yoshihiko Kawamoto

Hiroshi Sasaki

Nobuyuki Kobayashi

Kiyotaka Iwai

Akira Fusano

Tsuyoshi Takasaki

An engine with an exhaust treatment device () wherein a rotation moment of a side support stay () is generated by a load of a side portion () received by side support stay fastening tool () via an edge portion () of a cutout groove (). As a result, a load of the side portion () of the exhaust treatment device () can be supported by the side support stay (). A one-side temporary mount portions () is provided in a one-side support stay (). The one-side support stay () can be temporarily mounted on the one-side temporary mount portions ().

Engine with exhaust treatment device and attachment method for exhaust treatment device

The present invention relates to a compound of the following formula (I) or a pharmaceutically acceptable salt thereof, being useful as a renin inhibitor. [wherein Ris halogen, etc.; Ris H, etc.; Gis &#x2014;N(R)&#x2014;, etc.; Gis &#x2014;CO&#x2014;, etc.; Gis &#x2014;C(R)(R)&#x2014;, etc.; Gis oxygen, etc.; Ris optionally substituted Calkyl, etc.; Rand Rare independently the same or different, H, etc.; Ris H, optionally substituted Calkyl, etc.; R, R, Rc and Rare independently the same or different, and a group: -A-B (said A is single bond, etc., and said B is H, etc.), etc.; and n is 1, etc.]

Bicyclic heterocyclic derivative

Disclosed is a compound represented by the formula (1) below, a prodrug thereof or a pharmaceutically acceptable salt of either, which is useful as a therapeutic, preventive or ameliorating agent for diabetes and the like. (In the formula, Rrepresents an optionally substituted carbamoyl group or the like; X represents a hydroxyl group or the like; Wand Windependently represent a single bond or methylene; Rand Rindependently represent a hydrogen atom, an optionally substituted alkyl group or the like; and Ar represents an optionally substituted aryl group or the like.)

Oxindole derivative as feeding control agent

The blow-by gas that has flowed from a front-stage breather-chamber inlet () into a front-stage breather chamber () floats up around a preliminary valve-seat peripheral wall () and a preliminary breather-passage peripheral wall () and flows from a breather-chamber inlet () into a breather chamber (). When a breather-chamber peripheral wall () is removed from a breather-chamber attaching seat (), a diaphragm valve () is attached to the breather-chamber attaching seat () and has a valve face () seated on a preliminary valve seat (), and a plug () is taken out of a preliminary breather outlet (), from which a breather pipe () is led out, thereby enabling the front-stage breather chamber () to be used for a single-stage breather chamber provided with the diaphragm valve ().

Breather device for an engine

An engine comprises a crank case () provided with a lower opening portion (), which is covered with an oil pan () from below, and with a pair of left and right oil passages which extends in a front and rear direction along left and right lateral walls () and (). In this engine, the crank case () has the left and right lateral walls () and () provided with left and right ribs () and () extending in the front and rear direction. These left and right ribs () and () are raised inwards from the left and right lateral walls () and () of the crank case (). In order to provide left and right oil passages () and () in these left and right ribs () and (), these ribs () and () are positioned at the lower opening portion () of the crank case ().

Engine

A novel pyrrole derivative represented by the following formula (1) and a salt thereof: wherein Rmeans substituted alkenyl, etc.; Rmeans substituted benzoyl, etc.; and Rto Reach means hydrogen, alkyl, halogeno, etc. The derivative and salt have antidiabetic activity.

Pyrrole derivative

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Osaka, Japan

Kozo Yoshida