Osaka University

Nippon Zoki Pharmaceutical Co., Ltd.

Kousuke Baba

Mitsuru Naiki

Hideki Yoshikawa

Hideki Mochizuki

Hiroyuki Tanaka

Tsuyoshi Murase

Tsutomu Sasaki

Toru Iwahashi

An object is to provide a drug which is useful in treating a nervous system disease. A drug containing vitamin Bas an active ingredient according to the present invention has an M2 macrophage/microglia induction promoting effect, an M1 macrophage/microglia induction inhibiting effect, a nerve regeneration promoting effect, and the like and is very useful as a therapeutic agent for a nervous system disease, and particularly useful as a therapeutic agent for a central nervous system disease such as cerebral infarction, dementia, or spinal cord injury.

Therapeutic agent for nervous system disease

A method of treating a central nervous system disease, the method including administering an agent including a therapeutically effective amount of vitamin Bto a patient with a central nervous system disease to treat the central nervous system disease. This disclosure also relates to a method of promoting M2 macrophage/microglia induction, inhibiting M1 macrophage/microglia induction, and/or reducing the ratio of M1 macrophage/microglia to M2 macrophage/microglia in a patient in need thereof, the method including administering an agent including a therapeutically effective amount of vitamin Bto the patient to promote M2 macrophage/microglia induction, inhibit M1 macrophage/microglia induction, and/or reduce the ratio of M1 macrophage/microglia to M2 macrophage/microglia. This disclosure also relates to a pharmaceutical product including vitamin B.

Growing community of inventors

Suita, Japan

Kousuke Baba