Sumitomo Chemical Company, Limited

Kouji Yoshikawa

Makoto Itagaki

Toru Uekawa

Toshiyuki Kiji

Jun Ohshita

Ichiro Komoto

Ryo Minamida

Katsuhisa Masumoto

Koichi Nakazawa

Tomonori Yoshiyama

Toshio Somyo

Manabu Kashiwabara

A process for producing an optically active cyclopropanecarboxylic acid ester compound represented by the formula (4): (wherein R, Rand * each represents the same meaning as defined below), comprising reacting a diazoacetic acid ester represented by the formula (2):NCHCOR&#x2003;&#x2003;(2)(wherein Rrepresents an alkyl group having 1 to 15 carbon atoms or the like) with a compound represented by the formula (3): (wherein Rrepresents an alkyl group having 1 to 15 carbon atoms or the like), in the presence of an asymmetric copper complex obtained by reacting a copper compound and an optically active salicylideneaminoalcohol compound represented by the formula (1): (wherein Rrepresents an alkyl group having 1 to 4 carbon atoms or the like, Rrepresents a hydrogen atom or the like, Rand Rindependently represent a hydrogen atom or the like, and * represents an asymmetric center).

Method for producing optically active cyclopropane carboxylic acid ester compound, asymmetric copper complex, and optically active salicylideneaminoalcohol compound

A process for producing comprising reacting a 3-formyl-2,2-dimethylcyclopropanecarboxylate and propionitrile in the presence of a base to obtain 3-(2-cyano-1-propenyl)-2,2-dimethylcyclopropanecarboxylic acid or its salt.

Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof

A method for producing a cyclopropanecarboxylic acid compound represented by formula (VI)  

Method for producing cyclopropane carboxylic acid compound and intermediate therefor

A method for producing a purified formylcyclopropane compound represented by the formula (1) comprising (A) a step of reacting a crude formylcyclopropane compound represented by the formula (1):  

Method for producing purified formylcyclopropane compound and intermediate of such formylcyclopropane compound

A process for producing a trichloropyrimidine compound represented by the formula (2): wherein R represents a hydrogen atom etc., comprising reacting a dihydroxypyrimidine compound represented by the formula (1): wherein R represents the same meaning as above, with sulfuryl chloride and at least one chlorinating agent selected from the group consisting of hydrogen chloride, thionyl chloride, phosgene, phosphorus oxychloride, phosphorus pentachloride and phosphorus trichloride in the presence of an organic base.

Process for producing trichloropyrimidine compound

A method for producing an olefin compound represented by the formula (2): wherein Rand Rare the same or different, and independently represent an alkyl group or the like, with the proviso that Rand Rare not hydrogen atoms at the same time, Rrepresents an alkyl group or the like, which comprises contacting a palladium catalyst with an &#x3b1;,&#x3b2;-unsaturated aldehyde compound represented by the formula (1): wherein R, Rand Rare the same as defined above, in the presence of an inorganic base.

Method for producing olefin compound

A process for production of a trans-2,2-dimethyl-3-formylcyclopropanecarboxylic acid ester comprising:

Process for production of trans-2, 2-dimethyl-3-formylcyclopropanecarboxylic acid ester

A method for producing a (2-formyl-1-alkenyl)cyclopropane compound represented by the formula (1): wherein Rand Rare the same or different, and independently represent a hydrogen atom, an optionally substituted alkyl group, an optionally substituted alkenyl group, an optionally substituted alkynyl group, an optionally substituted aryl group or an optionally substituted aralkyl group,which comprises reacting a formylcyclopropane compound represented by the formula (3): wherein Ris the same as defined above, with an aldehyde compound represented by the formula (4): wherein Ris the same as defined above, in the presence of a base.

Method for producing (2-formyl-1-alkenyl) cyclopropane compound

A process for the production of a 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivative of formula (2): wherein R is hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted aralkyl, which process comprises reacting a 3,3-dimethyl-2-(2-methyl-1-propenyl)cyclopropanecarboxylic acid compound of formula (1): wherein R is as defined above, with a periodic acid compound in the presence of a ruthenium compound.

Process for production of 3,3-dimethyl-2-formylcyclopropanecarboxylic acid derivatives

It is provided that a method for preparing disodium paraperiodate, characterized in that a pH of a reaction mixture which is obtained by reacting sodium iodate, iodic acid or a mixture thereof with sodium hypochlorite using sodium hydroxide is adjusted to the range between 5 and 10.

Growing community of inventors

Toyonaka, Japan

Kouji Yoshikawa